Integrated Single-Cell and Transcriptome Sequencing Analyses Develop a Ubiquitination-Associated Signature in Gastric Cancer and Identified OTULIN as a Novel Biomarker
Background: Gastric cancer (GC) is the most commonly diagnosed digestive system malignancy with a dismal survival outcome. The prognostic value of ubiquitination-related genes (URGs) in GC has yet to be discovered. Methods: Two GC cohort datasets were obtained from the Cancer Genome Atlas Program (T...
Main Authors: | Zhongting Huang, Zhiyong Zhang, Yangyang Tu, Haibin He, Feng Qiu, Hailong Qian, Chunshu Pan |
---|---|
Format: | Article |
Language: | English |
Published: |
IMR Press
2023-11-01
|
Series: | Frontiers in Bioscience-Landmark |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/FBL/28/11/10.31083/j.fbl2811304 |
Similar Items
-
Compound heterozygous variants in OTULIN are associated with fulminant atypical late‐onset ORAS
by: Julia Zinngrebe, et al.
Published: (2022-03-01) -
An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity
by: Stephanie M. Almeida, et al.
Published: (2023-08-01) -
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation
by: Ruona Shi, et al.
Published: (2021-07-01) -
OTULIN couples WNT signaling to resistance in triple-negative breast cancer
by: Wei Wang, et al.
Published: (2020-11-01) -
Global Screening of LUBAC and OTULIN Interacting Proteins by Human Proteome Microarray
by: Lijie Zhou, et al.
Published: (2021-06-01)