STAT2 Limits Host Species Specificity of Human Metapneumovirus

The host tropism of viral infection is determined by a variety of factors, from cell surface receptors to innate immune signaling. Many viruses encode proteins that interfere with host innate immune recognition in order to promote infection. STAT2 is divergent between species and therefore has a rol...

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Bibliographic Details
Main Authors: Meredith C. Rogers, Margot Miranda-Katz, Yu Zhang, Tim D. Oury, Melissa B. Uccellini, Adolfo García-Sastre, John V. Williams
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/7/724