STAT2 Limits Host Species Specificity of Human Metapneumovirus
The host tropism of viral infection is determined by a variety of factors, from cell surface receptors to innate immune signaling. Many viruses encode proteins that interfere with host innate immune recognition in order to promote infection. STAT2 is divergent between species and therefore has a rol...
Main Authors: | Meredith C. Rogers, Margot Miranda-Katz, Yu Zhang, Tim D. Oury, Melissa B. Uccellini, Adolfo García-Sastre, John V. Williams |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
|
Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/12/7/724 |
Similar Items
-
Zoonotic Origins of Human Metapneumovirus: A Journey from Birds to Humans
by: Sonja T. Jesse, et al.
Published: (2022-03-01) -
Human metapneumovirus infection of organoid-derived human bronchial epithelium represents cell tropism and cytopathology as observed in in vivo models
by: Pau Ribó-Molina, et al.
Published: (2024-02-01) -
New Insights into the Host–Pathogen Interaction of <i>Mycoplasma gallisepticum</i> and Avian Metapneumovirus in Tracheal Organ Cultures of Chicken
by: Nancy Rüger, et al.
Published: (2021-11-01) -
IFN-λ drives distinct lung immune landscape changes and antiviral responses in human metapneumovirus infection
by: Jorna Sojati, et al.
Published: (2024-05-01) -
N4 DNA recognition by STAT6: structural and functional implications
by: Xiang Zhou, et al.
Published: (2017-02-01)