Noise processing by microRNA-mediated circuits: The Incoherent Feed-Forward Loop, revisited

The intrinsic stochasticity of gene expression is usually mitigated in higher eukaryotes by post-transcriptional regulation channels that stabilise the output layer, most notably protein levels. The discovery of small non-coding RNAs (miRNAs) in specific motifs of the genetic regulatory network has...

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Bibliographic Details
Main Authors: Silvia Grigolon, Francesca Di Patti, Andrea De Martino, Enzo Marinari
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844015305636