Advancements in Laser and Ultrasound Therapeutic Strategies for Cancer Cells: Recent Review

Cancer is a disease caused by uncontrollable cell growth and division. Surgery, chemotherapy, radiotherapy, and hormonotherapy are all cancer treatment options. In addition to noninvasive cancer ablative therapy. As an example, ultrasonic therapy, even with low-intensity pulsed ultrasound (LIPUS) o...

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Main Authors: Raghad Rasul, Jamal Abduljabbar, Iman Khalil
Format: Article
Language:English
Published: Al-Nahrain Journal for Engineering Sciences 2023-10-01
Series:مجلة النهرين للعلوم الهندسية
Subjects:
Online Access:https://nahje.com/index.php/main/article/view/1081
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author Raghad Rasul
Jamal Abduljabbar
Iman Khalil
author_facet Raghad Rasul
Jamal Abduljabbar
Iman Khalil
author_sort Raghad Rasul
collection DOAJ
description Cancer is a disease caused by uncontrollable cell growth and division. Surgery, chemotherapy, radiotherapy, and hormonotherapy are all cancer treatment options. In addition to noninvasive cancer ablative therapy. As an example, ultrasonic therapy, even with low-intensity pulsed ultrasound (LIPUS) or high-intensity focused ultrasound (HIFU), and Laser therapy (photo-biomodulation therapy) in low-level laser therapy (LLLT) with different wavelength ranges from ultraviolet (UV), visible and infrared (IR) that all have demonstrated different results depending on the target of treatment so previous trials therapies are being studied. This paper reviews recent studies on the in vitro treatment effect of ultrasound therapy and laser therapy on normal and cancerous cell lines with specific parameters. The effect of ultrasound results showed a decrease in cell proliferation and an increase in apoptosis in different types of cells, depending especially on sound intensity, known as Special Peak Temporal Average Intensity (ISPTA). While the laser effect is noticed on cell viability, either enhance or inhibit their viability depending upon the dose of exposure and other specific parameters like wavelength, energy density, and power density used in each treatment protocol. The previous studies conclude that each response would have a treatment method with specific parameters, even an increase or decrease in cell viability. Further studies need to be applying these methods in vivo.
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spelling doaj.art-07d91aadcd794006b6efe209e0802f812023-10-31T17:34:10ZengAl-Nahrain Journal for Engineering Sciencesمجلة النهرين للعلوم الهندسية2521-91542521-91622023-10-0126310.29194/NJES.26030226Advancements in Laser and Ultrasound Therapeutic Strategies for Cancer Cells: Recent ReviewRaghad Rasul0Jamal Abduljabbar1Iman Khalil2Al-Nahrain universityDept. of Biomedical Eng., College of Engineering, Al-Nahrain University, Baghdad-Iraq.Dept. of Biomedical Eng., College of Engineering, Al-Nahrain University, Baghdad-Iraq. Cancer is a disease caused by uncontrollable cell growth and division. Surgery, chemotherapy, radiotherapy, and hormonotherapy are all cancer treatment options. In addition to noninvasive cancer ablative therapy. As an example, ultrasonic therapy, even with low-intensity pulsed ultrasound (LIPUS) or high-intensity focused ultrasound (HIFU), and Laser therapy (photo-biomodulation therapy) in low-level laser therapy (LLLT) with different wavelength ranges from ultraviolet (UV), visible and infrared (IR) that all have demonstrated different results depending on the target of treatment so previous trials therapies are being studied. This paper reviews recent studies on the in vitro treatment effect of ultrasound therapy and laser therapy on normal and cancerous cell lines with specific parameters. The effect of ultrasound results showed a decrease in cell proliferation and an increase in apoptosis in different types of cells, depending especially on sound intensity, known as Special Peak Temporal Average Intensity (ISPTA). While the laser effect is noticed on cell viability, either enhance or inhibit their viability depending upon the dose of exposure and other specific parameters like wavelength, energy density, and power density used in each treatment protocol. The previous studies conclude that each response would have a treatment method with specific parameters, even an increase or decrease in cell viability. Further studies need to be applying these methods in vivo. https://nahje.com/index.php/main/article/view/1081Low-Intensity Pulsed UltrasoundHigh-Intensity Focused UltrasoundLaser TherapyCancer TreatmentIn-Vitro Treatment
spellingShingle Raghad Rasul
Jamal Abduljabbar
Iman Khalil
Advancements in Laser and Ultrasound Therapeutic Strategies for Cancer Cells: Recent Review
مجلة النهرين للعلوم الهندسية
Low-Intensity Pulsed Ultrasound
High-Intensity Focused Ultrasound
Laser Therapy
Cancer Treatment
In-Vitro Treatment
title Advancements in Laser and Ultrasound Therapeutic Strategies for Cancer Cells: Recent Review
title_full Advancements in Laser and Ultrasound Therapeutic Strategies for Cancer Cells: Recent Review
title_fullStr Advancements in Laser and Ultrasound Therapeutic Strategies for Cancer Cells: Recent Review
title_full_unstemmed Advancements in Laser and Ultrasound Therapeutic Strategies for Cancer Cells: Recent Review
title_short Advancements in Laser and Ultrasound Therapeutic Strategies for Cancer Cells: Recent Review
title_sort advancements in laser and ultrasound therapeutic strategies for cancer cells recent review
topic Low-Intensity Pulsed Ultrasound
High-Intensity Focused Ultrasound
Laser Therapy
Cancer Treatment
In-Vitro Treatment
url https://nahje.com/index.php/main/article/view/1081
work_keys_str_mv AT raghadrasul advancementsinlaserandultrasoundtherapeuticstrategiesforcancercellsrecentreview
AT jamalabduljabbar advancementsinlaserandultrasoundtherapeuticstrategiesforcancercellsrecentreview
AT imankhalil advancementsinlaserandultrasoundtherapeuticstrategiesforcancercellsrecentreview