White Cerebellum Sign: case series and literature review

Introduction: The white cerebellum sign is a rare radiological finding, seen in severe traumatic brain injury and severe hypoxia. Radiologically, it is characterized by cerebellar hyperdensity, associated with diffuse cerebral hemispheres hypoattenuation. This paper aims to guide the white cerebellu...

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Main Authors: Carlos Umberto Pereira, André Fabiano de Carvalho, Nicollas Nunes Rabelo, Gabriela Ferreira Kalkmann, Letícia Novak Crestani, Letícia Adrielle dos Santos
Format: Article
Language:English
Published: Brazilian Society for Pediatric Neurosurgery 2020-10-01
Series:Archives of Pediatric Neurosurgery
Subjects:
Online Access:https://www.archpedneurosurg.com.br/pkp/index.php/sbnped2019/article/view/51
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author Carlos Umberto Pereira
André Fabiano de Carvalho
Nicollas Nunes Rabelo
Gabriela Ferreira Kalkmann
Letícia Novak Crestani
Letícia Adrielle dos Santos
author_facet Carlos Umberto Pereira
André Fabiano de Carvalho
Nicollas Nunes Rabelo
Gabriela Ferreira Kalkmann
Letícia Novak Crestani
Letícia Adrielle dos Santos
author_sort Carlos Umberto Pereira
collection DOAJ
description Introduction: The white cerebellum sign is a rare radiological finding, seen in severe traumatic brain injury and severe hypoxia. Radiologically, it is characterized by cerebellar hyperdensity, associated with diffuse cerebral hemispheres hypoattenuation. This paper aims to guide the white cerebellum sign diagnosis in traumatic craniocerebral injuries or not in pediatric patients. Patients and Methods: The authors present a series of five cases that showed the white cerebellum sign from the period about 2007 and 2010, associated with a literature review. Results: The white cerebellum sign was present in 5 patients, three of them were male and 2 female. The mean age was 22 months. The causes of which were: traumatic brain injury (3), drowning (1) and metabolic encephalopathy (1). The skull computerized tomography scan was performed in all cases. All patients were submitted to conservative treatment. There were four deaths and one survived with severe neurological sequelae. Conclusion: The white cerebellum sign is associated with irreversible brain damage, and its pathophysiology is controversial. The imaging tests are important to diagnosis. It has a poor prognosis, associated with the development of diffuse cerebral atrophy or cystic encephalomalacia in those who survive.
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spelling doaj.art-07d931a344f34d39807756d04e572be62022-12-21T20:45:32ZengBrazilian Society for Pediatric NeurosurgeryArchives of Pediatric Neurosurgery2675-36262020-10-0123(September-December)e512020e51202010.46900/apn.v2i3(September-December).5152White Cerebellum Sign: case series and literature reviewCarlos Umberto Pereira0https://orcid.org/0000-0003-3263-721XAndré Fabiano de Carvalho1https://orcid.org/0000-0001-8064-5439Nicollas Nunes Rabelo2https://orcid.org/0000-0001-5238-8658Gabriela Ferreira Kalkmann3https://orcid.org/0000-0003-0040-7591Letícia Novak Crestani4https://orcid.org/0000-0002-4402-9660Letícia Adrielle dos Santos5https://orcid.org/0000-0001-6552-6642Departament of Neurosurgery, Sergipe Emergency Hospital. Preceptor of the Neurosurgery Residency at Surgery Hospital Charitable Foundation. Aracaju - Sergipe, Brasil.Radiologist of the Radiology Service at Sergipe Emergency Hospital and Sergipe Integrated Medicine Center. Aracaju - Sergipe, Brazil.Neurosurgeon. Neurosurgery Department. UniAtenas University Center. Paracatu - Minas Gerais, Brazil.Medical Students at Federal University of Paraná. Curitiba - Paraná, Brasil.Medical Student at Medicine Faculty of the Maringá University Center. Maringá - Paraná, Brasil.Medical Student at Federal University of Sergipe. Aracaju - Sergipe, Brasil.Introduction: The white cerebellum sign is a rare radiological finding, seen in severe traumatic brain injury and severe hypoxia. Radiologically, it is characterized by cerebellar hyperdensity, associated with diffuse cerebral hemispheres hypoattenuation. This paper aims to guide the white cerebellum sign diagnosis in traumatic craniocerebral injuries or not in pediatric patients. Patients and Methods: The authors present a series of five cases that showed the white cerebellum sign from the period about 2007 and 2010, associated with a literature review. Results: The white cerebellum sign was present in 5 patients, three of them were male and 2 female. The mean age was 22 months. The causes of which were: traumatic brain injury (3), drowning (1) and metabolic encephalopathy (1). The skull computerized tomography scan was performed in all cases. All patients were submitted to conservative treatment. There were four deaths and one survived with severe neurological sequelae. Conclusion: The white cerebellum sign is associated with irreversible brain damage, and its pathophysiology is controversial. The imaging tests are important to diagnosis. It has a poor prognosis, associated with the development of diffuse cerebral atrophy or cystic encephalomalacia in those who survive.https://www.archpedneurosurg.com.br/pkp/index.php/sbnped2019/article/view/51cerebellumneuroimagingprognosistraumatic brain injurywhite cerebellum sign
spellingShingle Carlos Umberto Pereira
André Fabiano de Carvalho
Nicollas Nunes Rabelo
Gabriela Ferreira Kalkmann
Letícia Novak Crestani
Letícia Adrielle dos Santos
White Cerebellum Sign: case series and literature review
Archives of Pediatric Neurosurgery
cerebellum
neuroimaging
prognosis
traumatic brain injury
white cerebellum sign
title White Cerebellum Sign: case series and literature review
title_full White Cerebellum Sign: case series and literature review
title_fullStr White Cerebellum Sign: case series and literature review
title_full_unstemmed White Cerebellum Sign: case series and literature review
title_short White Cerebellum Sign: case series and literature review
title_sort white cerebellum sign case series and literature review
topic cerebellum
neuroimaging
prognosis
traumatic brain injury
white cerebellum sign
url https://www.archpedneurosurg.com.br/pkp/index.php/sbnped2019/article/view/51
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AT nicollasnunesrabelo whitecerebellumsigncaseseriesandliteraturereview
AT gabrielaferreirakalkmann whitecerebellumsigncaseseriesandliteraturereview
AT leticianovakcrestani whitecerebellumsigncaseseriesandliteraturereview
AT leticiaadrielledossantos whitecerebellumsigncaseseriesandliteraturereview