White Cerebellum Sign: case series and literature review
Introduction: The white cerebellum sign is a rare radiological finding, seen in severe traumatic brain injury and severe hypoxia. Radiologically, it is characterized by cerebellar hyperdensity, associated with diffuse cerebral hemispheres hypoattenuation. This paper aims to guide the white cerebellu...
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Format: | Article |
Language: | English |
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Brazilian Society for Pediatric Neurosurgery
2020-10-01
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Series: | Archives of Pediatric Neurosurgery |
Subjects: | |
Online Access: | https://www.archpedneurosurg.com.br/pkp/index.php/sbnped2019/article/view/51 |
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author | Carlos Umberto Pereira André Fabiano de Carvalho Nicollas Nunes Rabelo Gabriela Ferreira Kalkmann Letícia Novak Crestani Letícia Adrielle dos Santos |
author_facet | Carlos Umberto Pereira André Fabiano de Carvalho Nicollas Nunes Rabelo Gabriela Ferreira Kalkmann Letícia Novak Crestani Letícia Adrielle dos Santos |
author_sort | Carlos Umberto Pereira |
collection | DOAJ |
description | Introduction: The white cerebellum sign is a rare radiological finding, seen in severe traumatic brain injury and severe hypoxia. Radiologically, it is characterized by cerebellar hyperdensity, associated with diffuse cerebral hemispheres hypoattenuation. This paper aims to guide the white cerebellum sign diagnosis in traumatic craniocerebral injuries or not in pediatric patients.
Patients and Methods: The authors present a series of five cases that showed the white cerebellum sign from the period about 2007 and 2010, associated with a literature review.
Results: The white cerebellum sign was present in 5 patients, three of them were male and 2 female. The mean age was 22 months. The causes of which were: traumatic brain injury (3), drowning (1) and metabolic encephalopathy (1). The skull computerized tomography scan was performed in all cases. All patients were submitted to conservative treatment. There were four deaths and one survived with severe neurological sequelae.
Conclusion: The white cerebellum sign is associated with irreversible brain damage, and its pathophysiology is controversial. The imaging tests are important to diagnosis. It has a poor prognosis, associated with the development of diffuse cerebral atrophy or cystic encephalomalacia in those who survive. |
first_indexed | 2024-12-19T00:21:23Z |
format | Article |
id | doaj.art-07d931a344f34d39807756d04e572be6 |
institution | Directory Open Access Journal |
issn | 2675-3626 |
language | English |
last_indexed | 2024-12-19T00:21:23Z |
publishDate | 2020-10-01 |
publisher | Brazilian Society for Pediatric Neurosurgery |
record_format | Article |
series | Archives of Pediatric Neurosurgery |
spelling | doaj.art-07d931a344f34d39807756d04e572be62022-12-21T20:45:32ZengBrazilian Society for Pediatric NeurosurgeryArchives of Pediatric Neurosurgery2675-36262020-10-0123(September-December)e512020e51202010.46900/apn.v2i3(September-December).5152White Cerebellum Sign: case series and literature reviewCarlos Umberto Pereira0https://orcid.org/0000-0003-3263-721XAndré Fabiano de Carvalho1https://orcid.org/0000-0001-8064-5439Nicollas Nunes Rabelo2https://orcid.org/0000-0001-5238-8658Gabriela Ferreira Kalkmann3https://orcid.org/0000-0003-0040-7591Letícia Novak Crestani4https://orcid.org/0000-0002-4402-9660Letícia Adrielle dos Santos5https://orcid.org/0000-0001-6552-6642Departament of Neurosurgery, Sergipe Emergency Hospital. Preceptor of the Neurosurgery Residency at Surgery Hospital Charitable Foundation. Aracaju - Sergipe, Brasil.Radiologist of the Radiology Service at Sergipe Emergency Hospital and Sergipe Integrated Medicine Center. Aracaju - Sergipe, Brazil.Neurosurgeon. Neurosurgery Department. UniAtenas University Center. Paracatu - Minas Gerais, Brazil.Medical Students at Federal University of Paraná. Curitiba - Paraná, Brasil.Medical Student at Medicine Faculty of the Maringá University Center. Maringá - Paraná, Brasil.Medical Student at Federal University of Sergipe. Aracaju - Sergipe, Brasil.Introduction: The white cerebellum sign is a rare radiological finding, seen in severe traumatic brain injury and severe hypoxia. Radiologically, it is characterized by cerebellar hyperdensity, associated with diffuse cerebral hemispheres hypoattenuation. This paper aims to guide the white cerebellum sign diagnosis in traumatic craniocerebral injuries or not in pediatric patients. Patients and Methods: The authors present a series of five cases that showed the white cerebellum sign from the period about 2007 and 2010, associated with a literature review. Results: The white cerebellum sign was present in 5 patients, three of them were male and 2 female. The mean age was 22 months. The causes of which were: traumatic brain injury (3), drowning (1) and metabolic encephalopathy (1). The skull computerized tomography scan was performed in all cases. All patients were submitted to conservative treatment. There were four deaths and one survived with severe neurological sequelae. Conclusion: The white cerebellum sign is associated with irreversible brain damage, and its pathophysiology is controversial. The imaging tests are important to diagnosis. It has a poor prognosis, associated with the development of diffuse cerebral atrophy or cystic encephalomalacia in those who survive.https://www.archpedneurosurg.com.br/pkp/index.php/sbnped2019/article/view/51cerebellumneuroimagingprognosistraumatic brain injurywhite cerebellum sign |
spellingShingle | Carlos Umberto Pereira André Fabiano de Carvalho Nicollas Nunes Rabelo Gabriela Ferreira Kalkmann Letícia Novak Crestani Letícia Adrielle dos Santos White Cerebellum Sign: case series and literature review Archives of Pediatric Neurosurgery cerebellum neuroimaging prognosis traumatic brain injury white cerebellum sign |
title | White Cerebellum Sign: case series and literature review |
title_full | White Cerebellum Sign: case series and literature review |
title_fullStr | White Cerebellum Sign: case series and literature review |
title_full_unstemmed | White Cerebellum Sign: case series and literature review |
title_short | White Cerebellum Sign: case series and literature review |
title_sort | white cerebellum sign case series and literature review |
topic | cerebellum neuroimaging prognosis traumatic brain injury white cerebellum sign |
url | https://www.archpedneurosurg.com.br/pkp/index.php/sbnped2019/article/view/51 |
work_keys_str_mv | AT carlosumbertopereira whitecerebellumsigncaseseriesandliteraturereview AT andrefabianodecarvalho whitecerebellumsigncaseseriesandliteraturereview AT nicollasnunesrabelo whitecerebellumsigncaseseriesandliteraturereview AT gabrielaferreirakalkmann whitecerebellumsigncaseseriesandliteraturereview AT leticianovakcrestani whitecerebellumsigncaseseriesandliteraturereview AT leticiaadrielledossantos whitecerebellumsigncaseseriesandliteraturereview |