Heterochromatin-dependent transcription of satellite DNAs in the Drosophila melanogaster female germline

Heterochromatin-dependent transcription of satellite DNAs in the Drosophila melanogaster female germline

Large blocks of tandemly repeated DNAs—satellite DNAs (satDNAs)—play important roles in heterochromatin formation and chromosome segregation. We know little about how satDNAs are regulated; however, their misregulation is associated with genomic instability and human diseases. We use the Drosophila...

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Bibliographic Details
Main Authors: Xiaolu Wei, Danna G Eickbush, Iain Speece, Amanda M Larracuente
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
satellite DNA
piRNAs
heterochromatin
ovary
testis
Online Access:https://elifesciences.org/articles/62375

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