Plumbagin modulates RANKL-induced osteoclast and osteoblast differentiation

Plumbagin modulates RANKL-induced osteoclast and osteoblast differentiation

Background: Bone remodeling is a balanced, dynamic function of two counteractive processes: osteoblasts-mediated bone formation and osteoclasts-dependent bone resorption. An imbalance between these two processes causes bone diseases. Herein, the effects and molecular modus operandi of plumbagin- a b...

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Bibliographic Details
Main Authors: Soni Ghumnani, Vitthal T. Barvkar, Suhas T. Mhaske, Bhaskar Saha, Richa Ashma
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Phytomedicine Plus
Subjects:
Bone cell differentiation
Plumbagin
MC3T3-E1 cell line
NFATc1
RNA sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031323000258

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http://www.sciencedirect.com/science/article/pii/S2667031323000258

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