Efficacy and safety of umbilical cord-derived mesenchymal stem cells in Chinese adults with type 2 diabetes: a single-center, double-blinded, randomized, placebo-controlled phase II trial

Efficacy and safety of umbilical cord-derived mesenchymal stem cells in Chinese adults with type 2 diabetes: a single-center, double-blinded, randomized, placebo-controlled phase II trial

Abstract Background To determine the efficacy and safety of umbilical cord-derived mesenchymal stem cells (UC-MSCs) in Chinese adults with type 2 diabetes mellitus (T2DM). Methods In this single-center, double-blinded, randomized, placebo-controlled phase II trial, 91 patients were randomly assigned...

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Bibliographic Details
Main Authors: Li Zang, Yijun Li, Haojie Hao, Jiejie Liu, Yu Cheng, Bing Li, Yaqi Yin, Qian Zhang, Fei Gao, Haibin Wang, Shi Gu, Jia Li, Fengxiang Lin, Yingfei Zhu, Guanglei Tian, Yulong Chen, Weijun Gu, Jin Du, Kang Chen, Qinghua Guo, Guoqing Yang, Yu Pei, Wenhua Yan, Xianling Wang, Junhua Meng, Saichun Zhang, Jianming Ba, Zhaohui Lyu, Jingtao Dou, Weidong Han, Yiming Mu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Stem Cell Research & Therapy
Subjects:
Type 2 diabetes mellitus
Umbilical cord-derived mesenchymal stem cells
Glycated hemoglobin A1c
Islet β-cell function
Insulin resistance
Online Access:https://doi.org/10.1186/s13287-022-02848-6

Internet

https://doi.org/10.1186/s13287-022-02848-6

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