Dysphagia is a strong predictor of death and functional dependence at three months post-stroke
ABSTRACT Background: Few Brazilian studies investigated risk factors for dysphagia and associated complications in a large cohort. Objective: To investigate frequency, predictors, and associated outcomes of dysphagia in patients up to three months post-stroke. Methods: Prospective cohort study...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
2022-02-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022005003210&tlng=en |
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| author | Aline Cristina PACHECO-CASTILHO Rubia Poliana Crisóstomo MIRANDA Ana Maria Queirós NORBERTO Diandra Bosi FAVORETTO Brunna Pileggi RIMOLI Luciana Bezerra de Mello ALVES Karina Tavares WEBER Taiza Elaine Grespan SANTOS Julio Cesar MORIGUTI João Pereira LEITE Roberto Oliveira DANTAS Rosemary MARTINO Octávio Marques PONTES-NETO |
| author_facet | Aline Cristina PACHECO-CASTILHO Rubia Poliana Crisóstomo MIRANDA Ana Maria Queirós NORBERTO Diandra Bosi FAVORETTO Brunna Pileggi RIMOLI Luciana Bezerra de Mello ALVES Karina Tavares WEBER Taiza Elaine Grespan SANTOS Julio Cesar MORIGUTI João Pereira LEITE Roberto Oliveira DANTAS Rosemary MARTINO Octávio Marques PONTES-NETO |
| author_sort | Aline Cristina PACHECO-CASTILHO |
| collection | DOAJ |
| description | ABSTRACT Background: Few Brazilian studies investigated risk factors for dysphagia and associated complications in a large cohort. Objective: To investigate frequency, predictors, and associated outcomes of dysphagia in patients up to three months post-stroke. Methods: Prospective cohort study of consecutively admitted patients in a specialized center for acute stroke. Patients with a transient ischemic attack, subarachnoid hemorrhage, cerebral venous thrombosis, hemorrhagic stroke with secondary cause, non-acute stroke, or those who did not consent to participate were excluded. Swallowing was evaluated by speech language pathologists using Volume-Viscosity Swallow Test. General function at three months post-stroke was assessed using the following instruments: Modified Rankin scale, Barthel Index and Functional Independence Measure. Results: A total of 831 patients were admitted and 305 patients were included according to the inclusion and exclusion criteria. The mean age of patients was 63.6±13.3 years, mean time from stroke to swallowing assessment was 4.2±4.1 days, and 45.2% of the patients had dysphagia. Age (OR=1.02; 95%CI 1.00-1.04; p=0.017), known medical history of obstructive sleep apnea (OR=5.13; 95%CI 1.74-15.15; p=0.003), and stroke severity at hospital admission (OR=1.10; 95%CI 1.06-1.15; p<0.001) were independently associated with dysphagia. Dysphagia (OR=3.78; 95%CI 2.16-6.61; p<0.001) and stroke severity (OR=1.05; 95%CI 1.00-1.09; p=0.024) were independently associated with death or functional dependence at three months. Conclusions: Dysphagia was present in almost half of stroke patients. Age, obstructive sleep apnea, and stroke severity were predictors of dysphagia, which was independently associated with death or functional dependence at three months. |
| first_indexed | 2024-12-19T12:34:53Z |
| format | Article |
| id | doaj.art-07efbdb7a4db4dec93cddbcbfd876d02 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-19T12:34:53Z |
| publishDate | 2022-02-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-07efbdb7a4db4dec93cddbcbfd876d022022-12-21T20:21:11ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272022-02-0110.1590/0004-282x-anp-2021-0127Dysphagia is a strong predictor of death and functional dependence at three months post-strokeAline Cristina PACHECO-CASTILHOhttps://orcid.org/0000-0003-2927-2766Rubia Poliana Crisóstomo MIRANDAhttps://orcid.org/0000-0001-8670-5308Ana Maria Queirós NORBERTOhttps://orcid.org/0000-0003-1544-2330Diandra Bosi FAVORETTOhttps://orcid.org/0000-0001-6853-1914Brunna Pileggi RIMOLIhttps://orcid.org/0000-0001-7434-3127Luciana Bezerra de Mello ALVEShttps://orcid.org/0000-0002-5068-3677Karina Tavares WEBERhttps://orcid.org/0000-0003-4907-8645Taiza Elaine Grespan SANTOShttps://orcid.org/0000-0003-3033-2981Julio Cesar MORIGUTIhttps://orcid.org/0000-0001-5499-3552João Pereira LEITEhttps://orcid.org/0000-0003-4240-2393Roberto Oliveira DANTAShttps://orcid.org/0000-0003-2183-0815Rosemary MARTINOhttps://orcid.org/0000-0002-3298-7714Octávio Marques PONTES-NETOhttps://orcid.org/0000-0003-0317-843XABSTRACT Background: Few Brazilian studies investigated risk factors for dysphagia and associated complications in a large cohort. Objective: To investigate frequency, predictors, and associated outcomes of dysphagia in patients up to three months post-stroke. Methods: Prospective cohort study of consecutively admitted patients in a specialized center for acute stroke. Patients with a transient ischemic attack, subarachnoid hemorrhage, cerebral venous thrombosis, hemorrhagic stroke with secondary cause, non-acute stroke, or those who did not consent to participate were excluded. Swallowing was evaluated by speech language pathologists using Volume-Viscosity Swallow Test. General function at three months post-stroke was assessed using the following instruments: Modified Rankin scale, Barthel Index and Functional Independence Measure. Results: A total of 831 patients were admitted and 305 patients were included according to the inclusion and exclusion criteria. The mean age of patients was 63.6±13.3 years, mean time from stroke to swallowing assessment was 4.2±4.1 days, and 45.2% of the patients had dysphagia. Age (OR=1.02; 95%CI 1.00-1.04; p=0.017), known medical history of obstructive sleep apnea (OR=5.13; 95%CI 1.74-15.15; p=0.003), and stroke severity at hospital admission (OR=1.10; 95%CI 1.06-1.15; p<0.001) were independently associated with dysphagia. Dysphagia (OR=3.78; 95%CI 2.16-6.61; p<0.001) and stroke severity (OR=1.05; 95%CI 1.00-1.09; p=0.024) were independently associated with death or functional dependence at three months. Conclusions: Dysphagia was present in almost half of stroke patients. Age, obstructive sleep apnea, and stroke severity were predictors of dysphagia, which was independently associated with death or functional dependence at three months.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022005003210&tlng=enDeglutitionDeglutition DisordersStrokeOutcome Assessment, Health Care |
| spellingShingle | Aline Cristina PACHECO-CASTILHO Rubia Poliana Crisóstomo MIRANDA Ana Maria Queirós NORBERTO Diandra Bosi FAVORETTO Brunna Pileggi RIMOLI Luciana Bezerra de Mello ALVES Karina Tavares WEBER Taiza Elaine Grespan SANTOS Julio Cesar MORIGUTI João Pereira LEITE Roberto Oliveira DANTAS Rosemary MARTINO Octávio Marques PONTES-NETO Dysphagia is a strong predictor of death and functional dependence at three months post-stroke Arquivos de Neuro-Psiquiatria Deglutition Deglutition Disorders Stroke Outcome Assessment, Health Care |
| title | Dysphagia is a strong predictor of death and functional dependence at three months post-stroke |
| title_full | Dysphagia is a strong predictor of death and functional dependence at three months post-stroke |
| title_fullStr | Dysphagia is a strong predictor of death and functional dependence at three months post-stroke |
| title_full_unstemmed | Dysphagia is a strong predictor of death and functional dependence at three months post-stroke |
| title_short | Dysphagia is a strong predictor of death and functional dependence at three months post-stroke |
| title_sort | dysphagia is a strong predictor of death and functional dependence at three months post stroke |
| topic | Deglutition Deglutition Disorders Stroke Outcome Assessment, Health Care |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2022005003210&tlng=en |
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