A Review of Bioactive Compounds and Antioxidant Activity Properties of <i>Piper</i> Species
Antioxidants are compounds that are able to inhibit the negative effects that come from free radicals. The phenomenon of imbalanced antioxidant production and the accumulation of free radicals in cells and tissues can cause oxidative stress. Excessive free radicals that enter the body cannot be ward...
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| Format: | Article |
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MDPI AG
2022-10-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/19/6774 |
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| author | Nono Carsono Sefren Geiner Tumilaar Dikdik Kurnia Diding Latipudin Mieke Hermiawati Satari |
| author_facet | Nono Carsono Sefren Geiner Tumilaar Dikdik Kurnia Diding Latipudin Mieke Hermiawati Satari |
| author_sort | Nono Carsono |
| collection | DOAJ |
| description | Antioxidants are compounds that are able to inhibit the negative effects that come from free radicals. The phenomenon of imbalanced antioxidant production and the accumulation of free radicals in cells and tissues can cause oxidative stress. Excessive free radicals that enter the body cannot be warded off by endogenous antioxidant compounds so that the required antioxidant compounds can come from the outside, which helps in the performance of endogenous antioxidants. Antioxidants that come from outside consist of synthetic and natural antioxidants; however, synthetic antioxidants are not an option because they have toxic and carcinogenic effects. Therefore, the use of natural ingredients is an alternative method that is needed to create a new natural antioxidant compound. <i>Piper</i> species are being considered as possible medicinal plants for the development of new sources of antioxidants. Several studies have been carried out starting from the extract levels, fractions, and compounds of the <i>Piper</i> species, which showed good antioxidant activity. Currently, some of these plants are being used as ingredients in traditional medicines to treat allergies, toothaches, and coughs. This review examines the distribution, botanical data, pharmacology, especially antioxidant activity, and the compounds contained in five <i>Piper</i> species, namely <i>Piper amalago</i> L., <i>Piper betle</i> L., <i>Piper hispidum</i> Sw., <i>Piper longum</i> L., and <i>Piper umbellatum</i> L. |
| first_indexed | 2024-03-09T21:22:22Z |
| format | Article |
| id | doaj.art-07f57061cead4e27a846a7e0ece69e50 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T21:22:22Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-07f57061cead4e27a846a7e0ece69e502023-11-23T21:17:05ZengMDPI AGMolecules1420-30492022-10-012719677410.3390/molecules27196774A Review of Bioactive Compounds and Antioxidant Activity Properties of <i>Piper</i> SpeciesNono Carsono0Sefren Geiner Tumilaar1Dikdik Kurnia2Diding Latipudin3Mieke Hermiawati Satari4Plant Breeding Laboratory, Faculty of Agriculture, Universitas Padjadjaran, Sumedang 45363, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Sumedang 45363, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Science, Universitas Padjadjaran, Sumedang 45363, IndonesiaDepartment of Animal Nutrition, Faculty of Animal Husbandry, Universitas Padjadjaran, Sumedang 45363, IndonesiaDepartment of Oral Biology, Faculty of Dentistry, Universitas Padjdajaran, Sumedang 45363, IndonesiaAntioxidants are compounds that are able to inhibit the negative effects that come from free radicals. The phenomenon of imbalanced antioxidant production and the accumulation of free radicals in cells and tissues can cause oxidative stress. Excessive free radicals that enter the body cannot be warded off by endogenous antioxidant compounds so that the required antioxidant compounds can come from the outside, which helps in the performance of endogenous antioxidants. Antioxidants that come from outside consist of synthetic and natural antioxidants; however, synthetic antioxidants are not an option because they have toxic and carcinogenic effects. Therefore, the use of natural ingredients is an alternative method that is needed to create a new natural antioxidant compound. <i>Piper</i> species are being considered as possible medicinal plants for the development of new sources of antioxidants. Several studies have been carried out starting from the extract levels, fractions, and compounds of the <i>Piper</i> species, which showed good antioxidant activity. Currently, some of these plants are being used as ingredients in traditional medicines to treat allergies, toothaches, and coughs. This review examines the distribution, botanical data, pharmacology, especially antioxidant activity, and the compounds contained in five <i>Piper</i> species, namely <i>Piper amalago</i> L., <i>Piper betle</i> L., <i>Piper hispidum</i> Sw., <i>Piper longum</i> L., and <i>Piper umbellatum</i> L.https://www.mdpi.com/1420-3049/27/19/6774antioxidant<i>Piper amalago</i><i>Piper betle</i><i>Piper hispidum</i><i>Piper longum</i><i>Piper umbellatum</i> |
| spellingShingle | Nono Carsono Sefren Geiner Tumilaar Dikdik Kurnia Diding Latipudin Mieke Hermiawati Satari A Review of Bioactive Compounds and Antioxidant Activity Properties of <i>Piper</i> Species Molecules antioxidant <i>Piper amalago</i> <i>Piper betle</i> <i>Piper hispidum</i> <i>Piper longum</i> <i>Piper umbellatum</i> |
| title | A Review of Bioactive Compounds and Antioxidant Activity Properties of <i>Piper</i> Species |
| title_full | A Review of Bioactive Compounds and Antioxidant Activity Properties of <i>Piper</i> Species |
| title_fullStr | A Review of Bioactive Compounds and Antioxidant Activity Properties of <i>Piper</i> Species |
| title_full_unstemmed | A Review of Bioactive Compounds and Antioxidant Activity Properties of <i>Piper</i> Species |
| title_short | A Review of Bioactive Compounds and Antioxidant Activity Properties of <i>Piper</i> Species |
| title_sort | review of bioactive compounds and antioxidant activity properties of i piper i species |
| topic | antioxidant <i>Piper amalago</i> <i>Piper betle</i> <i>Piper hispidum</i> <i>Piper longum</i> <i>Piper umbellatum</i> |
| url | https://www.mdpi.com/1420-3049/27/19/6774 |
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