Averting the legacy of kidney disease - focus on childhood

World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, in that the largest diagnostic group among children includes congenital anomalies and...

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Main Authors: J.R. Ingelfinger, K. Kalantar-Zadeh, F. Schaefer
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2016-01-01
Series:Brazilian Journal of Medical and Biological Research
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500303&lng=en&tlng=en
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author J.R. Ingelfinger
K. Kalantar-Zadeh
F. Schaefer
author_facet J.R. Ingelfinger
K. Kalantar-Zadeh
F. Schaefer
author_sort J.R. Ingelfinger
collection DOAJ
description World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, in that the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease as a consequence of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for-date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, although only a minority of children may require this ultimate intervention. Because there are disparities in access to care, effort is needed so that children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that the World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.
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spelling doaj.art-07f5d9d7ed7b45fba45b4dea6fbf36d72022-12-22T02:51:24ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research1414-431X2016-01-0149510.1590/1414-431X20165314S0100-879X2016000500303Averting the legacy of kidney disease - focus on childhoodJ.R. IngelfingerK. Kalantar-ZadehF. SchaeferWorld Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, in that the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease as a consequence of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for-date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, although only a minority of children may require this ultimate intervention. Because there are disparities in access to care, effort is needed so that children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that the World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500303&lng=en&tlng=en
spellingShingle J.R. Ingelfinger
K. Kalantar-Zadeh
F. Schaefer
Averting the legacy of kidney disease - focus on childhood
Brazilian Journal of Medical and Biological Research
title Averting the legacy of kidney disease - focus on childhood
title_full Averting the legacy of kidney disease - focus on childhood
title_fullStr Averting the legacy of kidney disease - focus on childhood
title_full_unstemmed Averting the legacy of kidney disease - focus on childhood
title_short Averting the legacy of kidney disease - focus on childhood
title_sort averting the legacy of kidney disease focus on childhood
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500303&lng=en&tlng=en
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