A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting
Genetic predisposition is one factor influencing interindividual drug response. Pharmacogenetic information can be used to guide the selection and dosing of certain drugs. However, the implementation of pharmacogenetics (PGx) in clinical practice remains challenging. Defining a formal structure, as...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Pharmacy |
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| Online Access: | https://www.mdpi.com/2226-4787/10/4/86 |
| _version_ | 1797408347782119424 |
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| author | Céline K. Stäuble Chiara Jeiziner Anna Bollinger Florine M. Wiss Martin Hatzinger Kurt E. Hersberger Thomas Ihde Markus L. Lampert Thorsten Mikoteit Henriette E. Meyer zu Schwabedissen Samuel S. Allemann |
| author_facet | Céline K. Stäuble Chiara Jeiziner Anna Bollinger Florine M. Wiss Martin Hatzinger Kurt E. Hersberger Thomas Ihde Markus L. Lampert Thorsten Mikoteit Henriette E. Meyer zu Schwabedissen Samuel S. Allemann |
| author_sort | Céline K. Stäuble |
| collection | DOAJ |
| description | Genetic predisposition is one factor influencing interindividual drug response. Pharmacogenetic information can be used to guide the selection and dosing of certain drugs. However, the implementation of pharmacogenetics (PGx) in clinical practice remains challenging. Defining a formal structure, as well as concrete procedures and clearly defined responsibilities, may facilitate and increase the use of PGx in clinical practice. Over 140 patient cases from an observational study in Switzerland formed the basis for the design and refinement of a pharmacist-led pharmacogenetics testing and counselling service (PGx service) in an interprofessional setting. Herein, we defined a six-step approach, including: (1) patient referral; (2) pre-test-counselling; (3) PGx testing; (4) medication review; (5) counselling; (6) follow-up. The six-step approach supports the importance of an interprofessional collaboration and the role of pharmacists in PGx testing and counselling across healthcare settings. |
| first_indexed | 2024-03-09T03:57:09Z |
| format | Article |
| id | doaj.art-07f761bc56374a8ab0b4a07076ec6e03 |
| institution | Directory Open Access Journal |
| issn | 2226-4787 |
| language | English |
| last_indexed | 2024-03-09T03:57:09Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmacy |
| spelling | doaj.art-07f761bc56374a8ab0b4a07076ec6e032023-12-03T14:18:20ZengMDPI AGPharmacy2226-47872022-07-011048610.3390/pharmacy10040086A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare SettingCéline K. Stäuble0Chiara Jeiziner1Anna Bollinger2Florine M. Wiss3Martin Hatzinger4Kurt E. Hersberger5Thomas Ihde6Markus L. Lampert7Thorsten Mikoteit8Henriette E. Meyer zu Schwabedissen9Samuel S. Allemann10Pharmaceutical Care, Department of Pharmaceutical Sciences, University of Basel, 4056 Basel, SwitzerlandPharmaceutical Care, Department of Pharmaceutical Sciences, University of Basel, 4056 Basel, SwitzerlandPharmaceutical Care, Department of Pharmaceutical Sciences, University of Basel, 4056 Basel, SwitzerlandPharmaceutical Care, Department of Pharmaceutical Sciences, University of Basel, 4056 Basel, SwitzerlandPsychiatric Services Solothurn, Solothurner Spitäler AG, Faculty of Medicine, University of Basel, 4503 Solothurn, SwitzerlandPharmaceutical Care, Department of Pharmaceutical Sciences, University of Basel, 4056 Basel, SwitzerlandInstitute of Psychiatry, Spitäler Frutigen Meiringen Interlaken AG (fmiAG), 3800 Unterseen, SwitzerlandPharmaceutical Care, Department of Pharmaceutical Sciences, University of Basel, 4056 Basel, SwitzerlandPsychiatric Services Solothurn, Solothurner Spitäler AG, Faculty of Medicine, University of Basel, 4503 Solothurn, SwitzerlandBiopharmacy, Department of Pharmaceutical Sciences, University of Basel, 4056 Basel, SwitzerlandPharmaceutical Care, Department of Pharmaceutical Sciences, University of Basel, 4056 Basel, SwitzerlandGenetic predisposition is one factor influencing interindividual drug response. Pharmacogenetic information can be used to guide the selection and dosing of certain drugs. However, the implementation of pharmacogenetics (PGx) in clinical practice remains challenging. Defining a formal structure, as well as concrete procedures and clearly defined responsibilities, may facilitate and increase the use of PGx in clinical practice. Over 140 patient cases from an observational study in Switzerland formed the basis for the design and refinement of a pharmacist-led pharmacogenetics testing and counselling service (PGx service) in an interprofessional setting. Herein, we defined a six-step approach, including: (1) patient referral; (2) pre-test-counselling; (3) PGx testing; (4) medication review; (5) counselling; (6) follow-up. The six-step approach supports the importance of an interprofessional collaboration and the role of pharmacists in PGx testing and counselling across healthcare settings.https://www.mdpi.com/2226-4787/10/4/86pharmaceutical careclinical pharmacymedication reviewpharmacy servicepharmacogenomicspersonalized medicine |
| spellingShingle | Céline K. Stäuble Chiara Jeiziner Anna Bollinger Florine M. Wiss Martin Hatzinger Kurt E. Hersberger Thomas Ihde Markus L. Lampert Thorsten Mikoteit Henriette E. Meyer zu Schwabedissen Samuel S. Allemann A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting Pharmacy pharmaceutical care clinical pharmacy medication review pharmacy service pharmacogenomics personalized medicine |
| title | A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting |
| title_full | A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting |
| title_fullStr | A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting |
| title_full_unstemmed | A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting |
| title_short | A Guide to a Pharmacist-Led Pharmacogenetic Testing and Counselling Service in an Interprofessional Healthcare Setting |
| title_sort | guide to a pharmacist led pharmacogenetic testing and counselling service in an interprofessional healthcare setting |
| topic | pharmaceutical care clinical pharmacy medication review pharmacy service pharmacogenomics personalized medicine |
| url | https://www.mdpi.com/2226-4787/10/4/86 |
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