The IRX3 Gene; the Missing Link between the FTO Gene and Obesity
Aims: The aim of this study was the investigation of the mediator role of the IRX3 gene in the relationship between the FTO gene and obesity. Materials and Methods: All related articles published in English from June 1990 to February 2017 were studied. Results: Only a Few studies have examined the a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
West Asia Organization for Cancer Prevention
2016-06-01
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| Series: | Asian Pacific Journal of Cancer Biology |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjcb/article/view/194 |
| _version_ | 1797341132727779328 |
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| author | Saeid Doaei Maryam Gholamalizadeh Alireza Mousavi Jarrahi Marjan Badakhanian Rahim Najafi |
| author_facet | Saeid Doaei Maryam Gholamalizadeh Alireza Mousavi Jarrahi Marjan Badakhanian Rahim Najafi |
| author_sort | Saeid Doaei |
| collection | DOAJ |
| description | Aims: The aim of this study was the investigation of the mediator role of the IRX3 gene in the relationship between the FTO gene and obesity.
Materials and Methods: All related articles published in English from June 1990 to February 2017 were studied.
Results: Only a Few studies have examined the association between the IRX3 gene with the FTO gene and obesity. However, all of them reported that the FTO gene can influence the IRX3 gene expression. Also, it’s reported that the IRX3 gene expression level has a significant association with body weight and body composition.
Conclusions: The FTO gene effects on obesity is in part due to its impact on the IRX3 gene expression level. The further studies are needed to investigate this interaction and clarify the existing mechanisms. |
| first_indexed | 2024-03-08T10:13:17Z |
| format | Article |
| id | doaj.art-07f76eb14d0b4a18926006f32e3eaa01 |
| institution | Directory Open Access Journal |
| issn | 2538-4635 |
| language | English |
| last_indexed | 2024-03-08T10:13:17Z |
| publishDate | 2016-06-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Cancer Biology |
| spelling | doaj.art-07f76eb14d0b4a18926006f32e3eaa012024-01-29T05:36:29ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Cancer Biology2538-46352016-06-0112333510.31557/apjcb.2016.1.2.33-35194The IRX3 Gene; the Missing Link between the FTO Gene and ObesitySaeid Doaei0Maryam GholamalizadehAlireza Mousavi Jarrahi1Marjan Badakhanian2Rahim Najafi3Students `Research Committee, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Faculty of Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Food Security Research Center and Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. 5Urmia University of Medical Sciences, Urmia, Iran.Urmia University of Medical Sciences, Urmia, Iran.Aims: The aim of this study was the investigation of the mediator role of the IRX3 gene in the relationship between the FTO gene and obesity. Materials and Methods: All related articles published in English from June 1990 to February 2017 were studied. Results: Only a Few studies have examined the association between the IRX3 gene with the FTO gene and obesity. However, all of them reported that the FTO gene can influence the IRX3 gene expression. Also, it’s reported that the IRX3 gene expression level has a significant association with body weight and body composition. Conclusions: The FTO gene effects on obesity is in part due to its impact on the IRX3 gene expression level. The further studies are needed to investigate this interaction and clarify the existing mechanisms.http://www.waocp.com/journal/index.php/apjcb/article/view/194irx3 gene, the fto gene, obesity |
| spellingShingle | Saeid Doaei Maryam Gholamalizadeh Alireza Mousavi Jarrahi Marjan Badakhanian Rahim Najafi The IRX3 Gene; the Missing Link between the FTO Gene and Obesity Asian Pacific Journal of Cancer Biology irx3 gene, the fto gene, obesity |
| title | The IRX3 Gene; the Missing Link between the FTO Gene and Obesity |
| title_full | The IRX3 Gene; the Missing Link between the FTO Gene and Obesity |
| title_fullStr | The IRX3 Gene; the Missing Link between the FTO Gene and Obesity |
| title_full_unstemmed | The IRX3 Gene; the Missing Link between the FTO Gene and Obesity |
| title_short | The IRX3 Gene; the Missing Link between the FTO Gene and Obesity |
| title_sort | irx3 gene the missing link between the fto gene and obesity |
| topic | irx3 gene, the fto gene, obesity |
| url | http://www.waocp.com/journal/index.php/apjcb/article/view/194 |
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