Green tea and metabolic syndrome: A 10-year research update review

Metabolic syndrome (MetS) has turned into a prevalent condition that has imposed a tremendous financial strain on public health care systems. It is believed that the MetS consists of four main factors (hypertension, dyslipidemia, hyperglycemia, and obesity) and may lead to cardiovascular events. Cam...

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Main Authors: Elahe Esmaeilpanah, Bibi Marjan Razavi, Hossein Hosseinzadeh
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2021-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_18678_132711f647b8438a1791aadc8f221424.pdf
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author Elahe Esmaeilpanah
Bibi Marjan Razavi
Hossein Hosseinzadeh
author_facet Elahe Esmaeilpanah
Bibi Marjan Razavi
Hossein Hosseinzadeh
author_sort Elahe Esmaeilpanah
collection DOAJ
description Metabolic syndrome (MetS) has turned into a prevalent condition that has imposed a tremendous financial strain on public health care systems. It is believed that the MetS consists of four main factors (hypertension, dyslipidemia, hyperglycemia, and obesity) and may lead to cardiovascular events. Camellia sinesis, in the form of green tea (GT), is one of the most consuming beverages worldwide. Catechins are the dominant component of green tea leaves. Epigallocatechin gallate has the maximum potency. GT has been widely used as a supplement in various health conditions. As the oxidative stress pathway is one of the probable mechanisms of MetS etiologies and GT beneficial effects, GT may be a novel strategy to overcome the MetS. This review aims to reveal the probable pharmacological effects of GT on MetS. The last 10-year original articles on MetS parameters and GT have been gathered in this review. This manuscript has summarized the probable effects of green tea and its catechins on MetS and focused on each different aspect of MetS separately, which can be used as a basis for further investigations for introducing effective compounds as a way to interfere with MetS.It seems that GT can reduce MetS parameters commonly via anti-inflammatory and anti-oxidative mechanisms. Further clinical trials are needed to confirm the use of GT and its constituents for the treatment of MetS.
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spelling doaj.art-07f7d4735fda431bb8bd193b6aff297f2022-12-21T20:06:51ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742021-09-012491159117210.22038/ijbms.2021.52980.1194318678Green tea and metabolic syndrome: A 10-year research update reviewElahe Esmaeilpanah0Bibi Marjan Razavi1Hossein Hosseinzadeh2Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranTargeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, IranPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, IranMetabolic syndrome (MetS) has turned into a prevalent condition that has imposed a tremendous financial strain on public health care systems. It is believed that the MetS consists of four main factors (hypertension, dyslipidemia, hyperglycemia, and obesity) and may lead to cardiovascular events. Camellia sinesis, in the form of green tea (GT), is one of the most consuming beverages worldwide. Catechins are the dominant component of green tea leaves. Epigallocatechin gallate has the maximum potency. GT has been widely used as a supplement in various health conditions. As the oxidative stress pathway is one of the probable mechanisms of MetS etiologies and GT beneficial effects, GT may be a novel strategy to overcome the MetS. This review aims to reveal the probable pharmacological effects of GT on MetS. The last 10-year original articles on MetS parameters and GT have been gathered in this review. This manuscript has summarized the probable effects of green tea and its catechins on MetS and focused on each different aspect of MetS separately, which can be used as a basis for further investigations for introducing effective compounds as a way to interfere with MetS.It seems that GT can reduce MetS parameters commonly via anti-inflammatory and anti-oxidative mechanisms. Further clinical trials are needed to confirm the use of GT and its constituents for the treatment of MetS.https://ijbms.mums.ac.ir/article_18678_132711f647b8438a1791aadc8f221424.pdfdiabetesdyslipidemiagreen teahypertensionmetabolic syndromeobesity
spellingShingle Elahe Esmaeilpanah
Bibi Marjan Razavi
Hossein Hosseinzadeh
Green tea and metabolic syndrome: A 10-year research update review
Iranian Journal of Basic Medical Sciences
diabetes
dyslipidemia
green tea
hypertension
metabolic syndrome
obesity
title Green tea and metabolic syndrome: A 10-year research update review
title_full Green tea and metabolic syndrome: A 10-year research update review
title_fullStr Green tea and metabolic syndrome: A 10-year research update review
title_full_unstemmed Green tea and metabolic syndrome: A 10-year research update review
title_short Green tea and metabolic syndrome: A 10-year research update review
title_sort green tea and metabolic syndrome a 10 year research update review
topic diabetes
dyslipidemia
green tea
hypertension
metabolic syndrome
obesity
url https://ijbms.mums.ac.ir/article_18678_132711f647b8438a1791aadc8f221424.pdf
work_keys_str_mv AT elaheesmaeilpanah greenteaandmetabolicsyndromea10yearresearchupdatereview
AT bibimarjanrazavi greenteaandmetabolicsyndromea10yearresearchupdatereview
AT hosseinhosseinzadeh greenteaandmetabolicsyndromea10yearresearchupdatereview