Clozapine-Induced Cardiovascular Side Effects and Autonomic Dysfunction: A Systematic Review

Clozapine-Induced Cardiovascular Side Effects and Autonomic Dysfunction: A Systematic Review

Background: Clozapine is the antipsychotic of choice for treatment-resistant schizophrenia and has minimal risk for extrapyramidal symptoms. Therapeutic benefits, however, are accompanied by a myriad of cardiometabolic side-effects. The specific reasons for clozapine's high propensity to cause...

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Bibliographic Details
Main Authors: Jessica W. Y. Yuen, David D. Kim, Ric M. Procyshyn, Randall F. White, William G. Honer, Alasdair M. Barr
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Neuroscience
Subjects:
clozapine
schizophrenia
autonomic
cardiovascular
catecholamine
heart rate
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2018.00203/full

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