Single-cell transcriptome atlas of the human corpus cavernosum
The corpus cavernosum is the most important structure for penile erection, and its dysfunction causes physiological and psychological problems. Here the authors perform single-cell RNA-sequencing on corpus cavernosum samples from males with normal erection and erectile dysfunction patients, providin...
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-31950-9 |
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author | LiangYu Zhao Sha Han HengChuan Su JianYing Li ErLei Zhi Peng Li ChenCheng Yao RuHui Tian HuiXing Chen HuiRong Chen JiaQiang Luo ChenKun Shi ZhiYong Ji JianLin Hu Gang Wu WeiDong Zhou YuXin Tang YuZhuo Chen GuiTing Lin Tom F. Lue DengLong Wu Zheng Li |
author_facet | LiangYu Zhao Sha Han HengChuan Su JianYing Li ErLei Zhi Peng Li ChenCheng Yao RuHui Tian HuiXing Chen HuiRong Chen JiaQiang Luo ChenKun Shi ZhiYong Ji JianLin Hu Gang Wu WeiDong Zhou YuXin Tang YuZhuo Chen GuiTing Lin Tom F. Lue DengLong Wu Zheng Li |
author_sort | LiangYu Zhao |
collection | DOAJ |
description | The corpus cavernosum is the most important structure for penile erection, and its dysfunction causes physiological and psychological problems. Here the authors perform single-cell RNA-sequencing on corpus cavernosum samples from males with normal erection and erectile dysfunction patients, providing insights into this pathology. |
first_indexed | 2024-04-12T08:23:55Z |
format | Article |
id | doaj.art-07fafce296174665a0ff8b6b174ec991 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-12T08:23:55Z |
publishDate | 2022-07-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-07fafce296174665a0ff8b6b174ec9912022-12-22T03:40:27ZengNature PortfolioNature Communications2041-17232022-07-0113111610.1038/s41467-022-31950-9Single-cell transcriptome atlas of the human corpus cavernosumLiangYu Zhao0Sha Han1HengChuan Su2JianYing Li3ErLei Zhi4Peng Li5ChenCheng Yao6RuHui Tian7HuiXing Chen8HuiRong Chen9JiaQiang Luo10ChenKun Shi11ZhiYong Ji12JianLin Hu13Gang Wu14WeiDong Zhou15YuXin Tang16YuZhuo Chen17GuiTing Lin18Tom F. Lue19DengLong Wu20Zheng Li21Department of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Urology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan UniversityDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Urology, Tongji Hospital, School of Medicine, Tongji UniversityDepartment of Urology, Tongji Hospital, School of Medicine, Tongji UniversityDepartment of Urology, Department of Interventional Medicine, Guangdong Provincial Key Laboratory of Biomedical Imaging, The Fifth Affiliated Hospital, Sun Yat-sen UniversityDepartment of Ultrasound, The Fifth Affiliated Hospital, Sun Yat-sen UniversityKnuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of CaliforniaKnuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of CaliforniaDepartment of Urology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan UniversityDepartment of Andrology, the Center for Men’s Health, Urologic Medical Center, Shanghai Key Laboratory of Reproductive Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineThe corpus cavernosum is the most important structure for penile erection, and its dysfunction causes physiological and psychological problems. Here the authors perform single-cell RNA-sequencing on corpus cavernosum samples from males with normal erection and erectile dysfunction patients, providing insights into this pathology.https://doi.org/10.1038/s41467-022-31950-9 |
spellingShingle | LiangYu Zhao Sha Han HengChuan Su JianYing Li ErLei Zhi Peng Li ChenCheng Yao RuHui Tian HuiXing Chen HuiRong Chen JiaQiang Luo ChenKun Shi ZhiYong Ji JianLin Hu Gang Wu WeiDong Zhou YuXin Tang YuZhuo Chen GuiTing Lin Tom F. Lue DengLong Wu Zheng Li Single-cell transcriptome atlas of the human corpus cavernosum Nature Communications |
title | Single-cell transcriptome atlas of the human corpus cavernosum |
title_full | Single-cell transcriptome atlas of the human corpus cavernosum |
title_fullStr | Single-cell transcriptome atlas of the human corpus cavernosum |
title_full_unstemmed | Single-cell transcriptome atlas of the human corpus cavernosum |
title_short | Single-cell transcriptome atlas of the human corpus cavernosum |
title_sort | single cell transcriptome atlas of the human corpus cavernosum |
url | https://doi.org/10.1038/s41467-022-31950-9 |
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