Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films
Surface chemical and biochemical functionalization is a fundamental process that is widely applied in many fields to add new functions, features, or capabilities to a material’s surface. Here, we demonstrate that surface acoustic waves (SAWs) can enhance the chemical functionalization of gold films....
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2017-10-01
|
| Series: | Sensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8220/17/11/2452 |
| _version_ | 1797999943606075392 |
|---|---|
| author | Gina Greco Matteo Agostini Richie Shilton Marco Travagliati Giovanni Signore Marco Cecchini |
| author_facet | Gina Greco Matteo Agostini Richie Shilton Marco Travagliati Giovanni Signore Marco Cecchini |
| author_sort | Gina Greco |
| collection | DOAJ |
| description | Surface chemical and biochemical functionalization is a fundamental process that is widely applied in many fields to add new functions, features, or capabilities to a material’s surface. Here, we demonstrate that surface acoustic waves (SAWs) can enhance the chemical functionalization of gold films. This is shown by using an integrated biochip composed by a microfluidic channel coupled to a surface plasmon resonance (SPR) readout system and by monitoring the adhesion of biotin-thiol on the gold SPR areas in different conditions. In the case of SAW-induced streaming, the functionalization efficiency is improved ≈ 5 times with respect to the case without SAWs. The technology here proposed can be easily applied to a wide variety of biological systems (e.g., proteins, nucleic acids) and devices (e.g., sensors, devices for cell cultures). |
| first_indexed | 2024-04-11T11:12:31Z |
| format | Article |
| id | doaj.art-07fbbabe48c946eab12acbdab5378db3 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T11:12:31Z |
| publishDate | 2017-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-07fbbabe48c946eab12acbdab5378db32022-12-22T04:27:24ZengMDPI AGSensors1424-82202017-10-011711245210.3390/s17112452s17112452Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold FilmsGina Greco0Matteo Agostini1Richie Shilton2Marco Travagliati3Giovanni Signore4Marco Cecchini5National Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyCenter for Nanotechnology Innovation@NEST, Istituto Italiano di Tecnologia, Piazza San Silvestro 12, 56127 Pisa, ItalyNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalyNational Enterprise for nanoScience and nanoTechnology (NEST), Istituto Nanoscienze-CNR and Scuola Normale Superiore, Piazza San Silvestro 12, 56127 Pisa, ItalySurface chemical and biochemical functionalization is a fundamental process that is widely applied in many fields to add new functions, features, or capabilities to a material’s surface. Here, we demonstrate that surface acoustic waves (SAWs) can enhance the chemical functionalization of gold films. This is shown by using an integrated biochip composed by a microfluidic channel coupled to a surface plasmon resonance (SPR) readout system and by monitoring the adhesion of biotin-thiol on the gold SPR areas in different conditions. In the case of SAW-induced streaming, the functionalization efficiency is improved ≈ 5 times with respect to the case without SAWs. The technology here proposed can be easily applied to a wide variety of biological systems (e.g., proteins, nucleic acids) and devices (e.g., sensors, devices for cell cultures).https://www.mdpi.com/1424-8220/17/11/2452functionalizationmicrofluidicssurface acoustic waves (SAWs) |
| spellingShingle | Gina Greco Matteo Agostini Richie Shilton Marco Travagliati Giovanni Signore Marco Cecchini Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films Sensors functionalization microfluidics surface acoustic waves (SAWs) |
| title | Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films |
| title_full | Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films |
| title_fullStr | Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films |
| title_full_unstemmed | Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films |
| title_short | Surface Acoustic Wave (SAW)-Enhanced Chemical Functionalization of Gold Films |
| title_sort | surface acoustic wave saw enhanced chemical functionalization of gold films |
| topic | functionalization microfluidics surface acoustic waves (SAWs) |
| url | https://www.mdpi.com/1424-8220/17/11/2452 |
| work_keys_str_mv | AT ginagreco surfaceacousticwavesawenhancedchemicalfunctionalizationofgoldfilms AT matteoagostini surfaceacousticwavesawenhancedchemicalfunctionalizationofgoldfilms AT richieshilton surfaceacousticwavesawenhancedchemicalfunctionalizationofgoldfilms AT marcotravagliati surfaceacousticwavesawenhancedchemicalfunctionalizationofgoldfilms AT giovannisignore surfaceacousticwavesawenhancedchemicalfunctionalizationofgoldfilms AT marcocecchini surfaceacousticwavesawenhancedchemicalfunctionalizationofgoldfilms |