Stereoscopic Integrated Imaging Goggles for Multimodal Intraoperative Image Guidance.
We have developed novel stereoscopic wearable multimodal intraoperative imaging and display systems entitled Integrated Imaging Goggles for guiding surgeries. The prototype systems offer real time stereoscopic fluorescence imaging and color reflectance imaging capacity, along with in vivo handheld m...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4631490?pdf=render |
| _version_ | 1818256366660222976 |
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| author | Christopher A Mela Carrie Patterson William K Thompson Francis Papay Yang Liu |
| author_facet | Christopher A Mela Carrie Patterson William K Thompson Francis Papay Yang Liu |
| author_sort | Christopher A Mela |
| collection | DOAJ |
| description | We have developed novel stereoscopic wearable multimodal intraoperative imaging and display systems entitled Integrated Imaging Goggles for guiding surgeries. The prototype systems offer real time stereoscopic fluorescence imaging and color reflectance imaging capacity, along with in vivo handheld microscopy and ultrasound imaging. With the Integrated Imaging Goggle, both wide-field fluorescence imaging and in vivo microscopy are provided. The real time ultrasound images can also be presented in the goggle display. Furthermore, real time goggle-to-goggle stereoscopic video sharing is demonstrated, which can greatly facilitate telemedicine. In this paper, the prototype systems are described, characterized and tested in surgeries in biological tissues ex vivo. We have found that the system can detect fluorescent targets with as low as 60 nM indocyanine green and can resolve structures down to 0.25 mm with large FOV stereoscopic imaging. The system has successfully guided simulated cancer surgeries in chicken. The Integrated Imaging Goggle is novel in 4 aspects: it is (a) the first wearable stereoscopic wide-field intraoperative fluorescence imaging and display system, (b) the first wearable system offering both large FOV and microscopic imaging simultaneously, |
| first_indexed | 2024-12-12T17:26:37Z |
| format | Article |
| id | doaj.art-07ff55c78e324ed59c43d6006a0679e2 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-12T17:26:37Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-07ff55c78e324ed59c43d6006a0679e22022-12-22T00:17:30ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-011011e014195610.1371/journal.pone.0141956Stereoscopic Integrated Imaging Goggles for Multimodal Intraoperative Image Guidance.Christopher A MelaCarrie PattersonWilliam K ThompsonFrancis PapayYang LiuWe have developed novel stereoscopic wearable multimodal intraoperative imaging and display systems entitled Integrated Imaging Goggles for guiding surgeries. The prototype systems offer real time stereoscopic fluorescence imaging and color reflectance imaging capacity, along with in vivo handheld microscopy and ultrasound imaging. With the Integrated Imaging Goggle, both wide-field fluorescence imaging and in vivo microscopy are provided. The real time ultrasound images can also be presented in the goggle display. Furthermore, real time goggle-to-goggle stereoscopic video sharing is demonstrated, which can greatly facilitate telemedicine. In this paper, the prototype systems are described, characterized and tested in surgeries in biological tissues ex vivo. We have found that the system can detect fluorescent targets with as low as 60 nM indocyanine green and can resolve structures down to 0.25 mm with large FOV stereoscopic imaging. The system has successfully guided simulated cancer surgeries in chicken. The Integrated Imaging Goggle is novel in 4 aspects: it is (a) the first wearable stereoscopic wide-field intraoperative fluorescence imaging and display system, (b) the first wearable system offering both large FOV and microscopic imaging simultaneously,http://europepmc.org/articles/PMC4631490?pdf=render |
| spellingShingle | Christopher A Mela Carrie Patterson William K Thompson Francis Papay Yang Liu Stereoscopic Integrated Imaging Goggles for Multimodal Intraoperative Image Guidance. PLoS ONE |
| title | Stereoscopic Integrated Imaging Goggles for Multimodal Intraoperative Image Guidance. |
| title_full | Stereoscopic Integrated Imaging Goggles for Multimodal Intraoperative Image Guidance. |
| title_fullStr | Stereoscopic Integrated Imaging Goggles for Multimodal Intraoperative Image Guidance. |
| title_full_unstemmed | Stereoscopic Integrated Imaging Goggles for Multimodal Intraoperative Image Guidance. |
| title_short | Stereoscopic Integrated Imaging Goggles for Multimodal Intraoperative Image Guidance. |
| title_sort | stereoscopic integrated imaging goggles for multimodal intraoperative image guidance |
| url | http://europepmc.org/articles/PMC4631490?pdf=render |
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