Epac2 activation mediates glucagon‐induced glucogenesis in primary rat hepatocytes
ABSTRACT Aims/Introduction Glucagon plays an essential role in hepatic glucogenesis by enhancing glycogen breakdown, inducing gluconeogenesis, and suppressing glycogenesis. Moreover, glucagon increases cyclic adenosine monophosphate (cAMP) levels, thereby activating protein kinase A (PKA) and cAMP g...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-04-01
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Series: | Journal of Diabetes Investigation |
Subjects: | |
Online Access: | https://doi.org/10.1111/jdi.14142 |