Sensitivity and specificity of Fenyö-Lindberg and Teicher scores in the diagnosis of acute appendicitis in women
The aim of the study was to assess diagnostic accuracy (sensitivity and specificity) of Fenyö-Lindberg and Teicher scores for distinguishing patients that need immediate surgical treatment from the others, in a female population from an urban setting. The study prospectively included 130 female pati...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2016-01-01
|
| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/262252 |
| _version_ | 1797207854266974208 |
|---|---|
| author | Zrinko Madžar Mario Kopljar Tomislav Madžar Marko Mesić Dubravka Mužina Mišić Slaven Čiček Mario Zovak |
| author_facet | Zrinko Madžar Mario Kopljar Tomislav Madžar Marko Mesić Dubravka Mužina Mišić Slaven Čiček Mario Zovak |
| author_sort | Zrinko Madžar |
| collection | DOAJ |
| description | The aim of the study was to assess diagnostic accuracy (sensitivity and specificity) of Fenyö-Lindberg and Teicher scores for distinguishing patients that need immediate surgical treatment from the others, in a female population from an urban setting. The study prospectively included 130 female patients admitted to the emergency department with abdominal pain indicating acute appendicitis. The scores and parameters of validity were calculated and compared to definitive diagnosis. For Fenyö-Lindberg score of -17 or less, 84.5% sensitivity, 55.6% specificity, 87.9% positive predictive value (PPV) and 48.4% negative predictive value (NPV) were recorded. For cut-off value greater or equal to -2, there was 59.2% sensitivity, 77.8% specificity, 91% PPV and 33.3% NPV. The Receiver Operating Characteristic (ROC) curve analysis of Fenyö-Lindberg score showed that the best single cut-off value for discriminating acute appendicitis in the study population was -15. For Teicher score, values greater than -3 yielded 89.3% sensitivity and 22.2% specificity, 81.4% PPV and 35.3% NPV. In conclusion, Fenyö-Lindberg score could be used as an additional tool to exclude appendicitis and avoid unnecessary appendectomies. Teicher score may help in recognizing patients with appendicitis. None of the two scores can indicate or decline appendectomy in all cases. Scoring systems may be useful for pointing to important clinical signs and symptoms in specific subpopulations. |
| first_indexed | 2024-04-24T09:29:31Z |
| format | Article |
| id | doaj.art-08097bb382114cfba0c8bde50dec5df6 |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-24T09:29:31Z |
| publishDate | 2016-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-08097bb382114cfba0c8bde50dec5df62024-04-15T14:04:46ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512016-01-0155.4.59359910.20471/acc.2016.55.04.09Sensitivity and specificity of Fenyö-Lindberg and Teicher scores in the diagnosis of acute appendicitis in womenZrinko Madžar0Mario Kopljar1Tomislav Madžar2Marko Mesić3Dubravka Mužina Mišić4Slaven Čiček5Mario Zovak6Clinical Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaClinical Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaSchool of Medicine, University of Zagreb, Zagreb, CroatiaClinical Department of Surgery, Zagreb Children's Hospital, Zagreb, CroatiaClinical Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaClinical Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaClinical Department of Surgery, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; School of Dental Medicine, University of Zagreb, Zagreb, CroatiaThe aim of the study was to assess diagnostic accuracy (sensitivity and specificity) of Fenyö-Lindberg and Teicher scores for distinguishing patients that need immediate surgical treatment from the others, in a female population from an urban setting. The study prospectively included 130 female patients admitted to the emergency department with abdominal pain indicating acute appendicitis. The scores and parameters of validity were calculated and compared to definitive diagnosis. For Fenyö-Lindberg score of -17 or less, 84.5% sensitivity, 55.6% specificity, 87.9% positive predictive value (PPV) and 48.4% negative predictive value (NPV) were recorded. For cut-off value greater or equal to -2, there was 59.2% sensitivity, 77.8% specificity, 91% PPV and 33.3% NPV. The Receiver Operating Characteristic (ROC) curve analysis of Fenyö-Lindberg score showed that the best single cut-off value for discriminating acute appendicitis in the study population was -15. For Teicher score, values greater than -3 yielded 89.3% sensitivity and 22.2% specificity, 81.4% PPV and 35.3% NPV. In conclusion, Fenyö-Lindberg score could be used as an additional tool to exclude appendicitis and avoid unnecessary appendectomies. Teicher score may help in recognizing patients with appendicitis. None of the two scores can indicate or decline appendectomy in all cases. Scoring systems may be useful for pointing to important clinical signs and symptoms in specific subpopulations.https://hrcak.srce.hr/file/262252Appendicitis – diagnosisWomenSensitivitySpecificityROC curvePredictive value |
| spellingShingle | Zrinko Madžar Mario Kopljar Tomislav Madžar Marko Mesić Dubravka Mužina Mišić Slaven Čiček Mario Zovak Sensitivity and specificity of Fenyö-Lindberg and Teicher scores in the diagnosis of acute appendicitis in women Acta Clinica Croatica Appendicitis – diagnosis Women Sensitivity Specificity ROC curve Predictive value |
| title | Sensitivity and specificity of Fenyö-Lindberg and Teicher scores in the diagnosis of acute appendicitis in women |
| title_full | Sensitivity and specificity of Fenyö-Lindberg and Teicher scores in the diagnosis of acute appendicitis in women |
| title_fullStr | Sensitivity and specificity of Fenyö-Lindberg and Teicher scores in the diagnosis of acute appendicitis in women |
| title_full_unstemmed | Sensitivity and specificity of Fenyö-Lindberg and Teicher scores in the diagnosis of acute appendicitis in women |
| title_short | Sensitivity and specificity of Fenyö-Lindberg and Teicher scores in the diagnosis of acute appendicitis in women |
| title_sort | sensitivity and specificity of fenyo lindberg and teicher scores in the diagnosis of acute appendicitis in women |
| topic | Appendicitis – diagnosis Women Sensitivity Specificity ROC curve Predictive value |
| url | https://hrcak.srce.hr/file/262252 |
| work_keys_str_mv | AT zrinkomadzar sensitivityandspecificityoffenyolindbergandteicherscoresinthediagnosisofacuteappendicitisinwomen AT mariokopljar sensitivityandspecificityoffenyolindbergandteicherscoresinthediagnosisofacuteappendicitisinwomen AT tomislavmadzar sensitivityandspecificityoffenyolindbergandteicherscoresinthediagnosisofacuteappendicitisinwomen AT markomesic sensitivityandspecificityoffenyolindbergandteicherscoresinthediagnosisofacuteappendicitisinwomen AT dubravkamuzinamisic sensitivityandspecificityoffenyolindbergandteicherscoresinthediagnosisofacuteappendicitisinwomen AT slavencicek sensitivityandspecificityoffenyolindbergandteicherscoresinthediagnosisofacuteappendicitisinwomen AT mariozovak sensitivityandspecificityoffenyolindbergandteicherscoresinthediagnosisofacuteappendicitisinwomen |