Association of dengue virus‐specific polyfunctional T‐cell responses with clinical disease severity in acute dengue infection

Association of dengue virus‐specific polyfunctional T‐cell responses with clinical disease severity in acute dengue infection

Abstract Introduction Although the role of dengue virus (DENV)‐specific T cells in the pathogenesis of acute dengue infection is emerging, the functionality of virus‐specific T cells associated with milder clinical disease has not been well studied. We sought to investigate how the functionality of...

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Main Authors: Dulharie T. Wijeratne, Samitha Fernando, Laksiri Gomes, Chandima Jeewandara, Geethal Jayarathna, Yashoda Perera, Samurdhi Wickramanayake, Ananda Wijewickrama, Graham S. Ogg, Gathsaurie N. Malavige
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Immunity, Inflammation and Disease
Subjects:
clinical disease severity
cytokines
dengue
polyfunctional T cells
Online Access:https://doi.org/10.1002/iid3.271

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