An overview of Human Papillomavirus (HPV) as an etiological factor of the anal cancer

Human papillomavirus (HPV) is a DNA tumour virus that is the primary cause of sexually transmitted infections (STIs). The direct connection between HPV and cervical cancer was discovered in 1980, however, many physicians and the general public are still oblivious to the association of HPV and anal c...

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Main Authors: Joanna Krzowska-Firych, Georgia Lucas, Christiana Lucas, Nicholas Lucas, Łukasz Pietrzyk
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Infection and Public Health
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034118301011
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author Joanna Krzowska-Firych
Georgia Lucas
Christiana Lucas
Nicholas Lucas
Łukasz Pietrzyk
author_facet Joanna Krzowska-Firych
Georgia Lucas
Christiana Lucas
Nicholas Lucas
Łukasz Pietrzyk
author_sort Joanna Krzowska-Firych
collection DOAJ
description Human papillomavirus (HPV) is a DNA tumour virus that is the primary cause of sexually transmitted infections (STIs). The direct connection between HPV and cervical cancer was discovered in 1980, however, many physicians and the general public are still oblivious to the association of HPV and anal cancer; most individuals find out about this relationship after a confirmed diagnosis, and therefore, it is important to raise awareness about HPV as an etiological agent in anal cancer. There is a quadrivalent vaccine available, which prevents an individual from being infected with HPV, thus anal cancer is mainly a preventable cancer when caused by HPV, and ultimately, preventing cancer is better than curing cancer, especially when there is no definite cure.This article aims to review the microbiology, pathophysiology, epidemiology, clinical presentation, diagnostic evaluation, prophylaxis and treatment options for HPV as an etiology agent in anal cancers in light of recent literature.
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spelling doaj.art-080b746b7def43a2a9dec0b84b93a5052022-12-22T00:13:35ZengElsevierJournal of Infection and Public Health1876-03412019-01-0112116An overview of Human Papillomavirus (HPV) as an etiological factor of the anal cancerJoanna Krzowska-Firych0Georgia Lucas1Christiana Lucas2Nicholas Lucas3Łukasz Pietrzyk4Department of Infectious Diseases, Medical University of Lublin, Poland; Clinical Research Association for Infectious Disease at the Department of Infectious Diseases, Medical University of Lublin, PolandClinical Research Association for Infectious Disease at the Department of Infectious Diseases, Medical University of Lublin, PolandClinical Research Association for Infectious Disease at the Department of Infectious Diseases, Medical University of Lublin, PolandClinical Research Association for Infectious Disease at the Department of Infectious Diseases, Medical University of Lublin, PolandDepartment of General, Oncological and Minimally Invasive Surgery, 1st Military Clinical Hospital with the Outpatient Clinic in Lublin, Poland; Department of Didactics and Medical Simulation, Chair of Anatomy, Medical University of Lublin, Poland; Corresponding author.Human papillomavirus (HPV) is a DNA tumour virus that is the primary cause of sexually transmitted infections (STIs). The direct connection between HPV and cervical cancer was discovered in 1980, however, many physicians and the general public are still oblivious to the association of HPV and anal cancer; most individuals find out about this relationship after a confirmed diagnosis, and therefore, it is important to raise awareness about HPV as an etiological agent in anal cancer. There is a quadrivalent vaccine available, which prevents an individual from being infected with HPV, thus anal cancer is mainly a preventable cancer when caused by HPV, and ultimately, preventing cancer is better than curing cancer, especially when there is no definite cure.This article aims to review the microbiology, pathophysiology, epidemiology, clinical presentation, diagnostic evaluation, prophylaxis and treatment options for HPV as an etiology agent in anal cancers in light of recent literature.http://www.sciencedirect.com/science/article/pii/S1876034118301011
spellingShingle Joanna Krzowska-Firych
Georgia Lucas
Christiana Lucas
Nicholas Lucas
Łukasz Pietrzyk
An overview of Human Papillomavirus (HPV) as an etiological factor of the anal cancer
Journal of Infection and Public Health
title An overview of Human Papillomavirus (HPV) as an etiological factor of the anal cancer
title_full An overview of Human Papillomavirus (HPV) as an etiological factor of the anal cancer
title_fullStr An overview of Human Papillomavirus (HPV) as an etiological factor of the anal cancer
title_full_unstemmed An overview of Human Papillomavirus (HPV) as an etiological factor of the anal cancer
title_short An overview of Human Papillomavirus (HPV) as an etiological factor of the anal cancer
title_sort overview of human papillomavirus hpv as an etiological factor of the anal cancer
url http://www.sciencedirect.com/science/article/pii/S1876034118301011
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