Structural and dynamic basis of substrate permissiveness in hydroxycinnamoyltransferase (HCT).
Substrate permissiveness has long been regarded as the raw materials for the evolution of new enzymatic functions. In land plants, hydroxycinnamoyltransferase (HCT) is an essential enzyme of the phenylpropanoid metabolism. Although essential enzymes are normally associated with high substrate specif...
Main Authors: | Ying-Chih Chiang, Olesya Levsh, Chun Kei Lam, Jing-Ke Weng, Yi Wang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-10-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC6203249?pdf=render |
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