AlphaFold and the future of structural biology
This editorial acknowledges the transformative impact of new machine-learning methods, such as the use of AlphaFold, but also makes the case for the continuing need for experimental structural biology.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2023-07-01
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| Series: | IUCrJ |
| Subjects: | |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S2052252523004943 |
| _version_ | 1797785840234004480 |
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| author | Randy J. Read Edward N. Baker Charles S. Bond Elspeth F. Garman Mark J. van Raaij |
| author_facet | Randy J. Read Edward N. Baker Charles S. Bond Elspeth F. Garman Mark J. van Raaij |
| author_sort | Randy J. Read |
| collection | DOAJ |
| description | This editorial acknowledges the transformative impact of new machine-learning methods, such as the use of AlphaFold, but also makes the case for the continuing need for experimental structural biology. |
| first_indexed | 2024-03-13T00:59:40Z |
| format | Article |
| id | doaj.art-08110045186d4245962bb14f4413bfb6 |
| institution | Directory Open Access Journal |
| issn | 2052-2525 |
| language | English |
| last_indexed | 2024-03-13T00:59:40Z |
| publishDate | 2023-07-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | IUCrJ |
| spelling | doaj.art-08110045186d4245962bb14f4413bfb62023-07-06T13:03:09ZengInternational Union of CrystallographyIUCrJ2052-25252023-07-0110437737910.1107/S2052252523004943me6233AlphaFold and the future of structural biologyRandy J. Read0Edward N. Baker1Charles S. Bond2Elspeth F. Garman3Mark J. van Raaij4Cambridge Institute for Medical Research, University of Cambridge, The Keith Peters Building, Hills Road, Cambridge CB2 0XY, United KingdomSchool of Biological Sciences, University of Auckland, Auckland, New ZealandSchool of Molecular Sciences, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, AustraliaDepartment of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford OX1 3QU, United KingdomDepartamento de Estructura de Macromoleculas, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones Cientificas, 28049 Madrid, SpainThis editorial acknowledges the transformative impact of new machine-learning methods, such as the use of AlphaFold, but also makes the case for the continuing need for experimental structural biology.http://scripts.iucr.org/cgi-bin/paper?S2052252523004943alphafoldprotein structure predictioncrystallographycryo-em |
| spellingShingle | Randy J. Read Edward N. Baker Charles S. Bond Elspeth F. Garman Mark J. van Raaij AlphaFold and the future of structural biology IUCrJ alphafold protein structure prediction crystallography cryo-em |
| title | AlphaFold and the future of structural biology |
| title_full | AlphaFold and the future of structural biology |
| title_fullStr | AlphaFold and the future of structural biology |
| title_full_unstemmed | AlphaFold and the future of structural biology |
| title_short | AlphaFold and the future of structural biology |
| title_sort | alphafold and the future of structural biology |
| topic | alphafold protein structure prediction crystallography cryo-em |
| url | http://scripts.iucr.org/cgi-bin/paper?S2052252523004943 |
| work_keys_str_mv | AT randyjread alphafoldandthefutureofstructuralbiology AT edwardnbaker alphafoldandthefutureofstructuralbiology AT charlessbond alphafoldandthefutureofstructuralbiology AT elspethfgarman alphafoldandthefutureofstructuralbiology AT markjvanraaij alphafoldandthefutureofstructuralbiology |