Segmentation of meibomian glands based on deep learning

AIM: To explore the application value of deep learning technology in automatic meibomian glands segmentation. METHODS:Infrared meibomian gland images were collected and 193 of them were picked out for establishing the database. The images were manually labeled by three clinicians. UNet++ network and...

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Main Authors: Jia-Wen Lin, Zhi-Ming Lin, Tai-Chen Lai, Lin-Ling Guo, Jing Zou, Li Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2022-07-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2022/7/202207025.pdf
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author Jia-Wen Lin
Zhi-Ming Lin
Tai-Chen Lai
Lin-Ling Guo
Jing Zou
Li Li
author_facet Jia-Wen Lin
Zhi-Ming Lin
Tai-Chen Lai
Lin-Ling Guo
Jing Zou
Li Li
author_sort Jia-Wen Lin
collection DOAJ
description AIM: To explore the application value of deep learning technology in automatic meibomian glands segmentation. METHODS:Infrared meibomian gland images were collected and 193 of them were picked out for establishing the database. The images were manually labeled by three clinicians. UNet++ network and automatic data expansion strategy were introduced to construct the automatic meibomian glands segmentation model. The feasibility and effectiveness of the proposed segmentation model were analyzed by precision, sensitivity, specificity, accuracy and intersection over union.RESULTS: Taking manual labeling as the gold standard, the presented method segment the glands effectively and steadily with accuracy, sensitivity and specificity of 94.31%, 82.15% and 96.13% respectively. On the average, only 0.11s was taken for glands segmentation of single image.CONCLUSIONS: In this paper, deep learning technology is introduced to realize automatic segmentation of meibomian glands, achieving high accuracy, good stability and efficiency. It would be quite useful for calculation of gland morphological parameters, the clinical diagnosis and screening of related diseases, improving the diagnostic efficiency.
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spelling doaj.art-081261208f304b8abbdab0fcea31ad7d2022-12-22T00:32:01ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232022-07-012271191119410.3980/j.issn.1672-5123.2022.7.25202207025Segmentation of meibomian glands based on deep learningJia-Wen Lin0Zhi-Ming Lin1Tai-Chen Lai2Lin-Ling Guo3Jing Zou4Li Li5College of Computer and Data Science, Fuzhou University, Fuzhou 350108, Fujian Province, China; Fujian Provincial Key Laboratory of Networking Computing and Intelligent Information Processing, Fuzhou University, Fuzhou 350108, Fujian Province, ChinaCollege of Computer and Data Science, Fuzhou University, Fuzhou 350108, Fujian Province, China; Fujian Provincial Key Laboratory of Networking Computing and Intelligent Information Processing, Fuzhou University, Fuzhou 350108, Fujian Province, ChinaSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou 350108, Fujian Province, ChinaSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou 350108, Fujian Province, ChinaSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou 350108, Fujian Province, ChinaDepartment of Ophthalmology, Fujian Provincial Hospital, Fuzhou 350002, Fujian Province, China; Department of Ophthalmology, Fujian Provincial Hospital South Branch, Fuzhou 350002, Fujian Province, ChinaAIM: To explore the application value of deep learning technology in automatic meibomian glands segmentation. METHODS:Infrared meibomian gland images were collected and 193 of them were picked out for establishing the database. The images were manually labeled by three clinicians. UNet++ network and automatic data expansion strategy were introduced to construct the automatic meibomian glands segmentation model. The feasibility and effectiveness of the proposed segmentation model were analyzed by precision, sensitivity, specificity, accuracy and intersection over union.RESULTS: Taking manual labeling as the gold standard, the presented method segment the glands effectively and steadily with accuracy, sensitivity and specificity of 94.31%, 82.15% and 96.13% respectively. On the average, only 0.11s was taken for glands segmentation of single image.CONCLUSIONS: In this paper, deep learning technology is introduced to realize automatic segmentation of meibomian glands, achieving high accuracy, good stability and efficiency. It would be quite useful for calculation of gland morphological parameters, the clinical diagnosis and screening of related diseases, improving the diagnostic efficiency.http://ies.ijo.cn/cn_publish/2022/7/202207025.pdfmeibomian gland dysfunctioninfrared meibomian gland imagesgland segmentationdeep learningunet++
spellingShingle Jia-Wen Lin
Zhi-Ming Lin
Tai-Chen Lai
Lin-Ling Guo
Jing Zou
Li Li
Segmentation of meibomian glands based on deep learning
Guoji Yanke Zazhi
meibomian gland dysfunction
infrared meibomian gland images
gland segmentation
deep learning
unet++
title Segmentation of meibomian glands based on deep learning
title_full Segmentation of meibomian glands based on deep learning
title_fullStr Segmentation of meibomian glands based on deep learning
title_full_unstemmed Segmentation of meibomian glands based on deep learning
title_short Segmentation of meibomian glands based on deep learning
title_sort segmentation of meibomian glands based on deep learning
topic meibomian gland dysfunction
infrared meibomian gland images
gland segmentation
deep learning
unet++
url http://ies.ijo.cn/cn_publish/2022/7/202207025.pdf
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AT taichenlai segmentationofmeibomianglandsbasedondeeplearning
AT linlingguo segmentationofmeibomianglandsbasedondeeplearning
AT jingzou segmentationofmeibomianglandsbasedondeeplearning
AT lili segmentationofmeibomianglandsbasedondeeplearning