Calcium Signals from the Vacuole
The vacuole is by far the largest intracellular Ca2+ store in most plant cells. Here, the current knowledge about the molecular mechanisms of vacuolar Ca2+ release and Ca2+ uptake is summarized, and how different vacuolar Ca2+ channels and Ca2+ pumps may contribute to Ca2+ signaling in plant cells i...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2013-10-01
|
| Series: | Plants |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2223-7747/2/4/589 |
| _version_ | 1818960098079277056 |
|---|---|
| author | Gerald Schönknecht |
| author_facet | Gerald Schönknecht |
| author_sort | Gerald Schönknecht |
| collection | DOAJ |
| description | The vacuole is by far the largest intracellular Ca2+ store in most plant cells. Here, the current knowledge about the molecular mechanisms of vacuolar Ca2+ release and Ca2+ uptake is summarized, and how different vacuolar Ca2+ channels and Ca2+ pumps may contribute to Ca2+ signaling in plant cells is discussed. To provide a phylogenetic perspective, the distribution of potential vacuolar Ca2+ transporters is compared for different clades of photosynthetic eukaryotes. There are several candidates for vacuolar Ca2+ channels that could elicit cytosolic [Ca2+] transients. Typical second messengers, such as InsP3 and cADPR, seem to trigger vacuolar Ca2+ release, but the molecular mechanism of this Ca2+ release still awaits elucidation. Some vacuolar Ca2+ channels have been identified on a molecular level, the voltage-dependent SV/TPC1 channel, and recently two cyclic-nucleotide-gated cation channels. However, their function in Ca2+ signaling still has to be demonstrated. Ca2+ pumps in addition to establishing long-term Ca2+ homeostasis can shape cytosolic [Ca2+] transients by limiting their amplitude and duration, and may thus affect Ca2+ signaling. |
| first_indexed | 2024-12-20T11:52:08Z |
| format | Article |
| id | doaj.art-0812d5d7867d4e5893ed5e656becf86f |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-12-20T11:52:08Z |
| publishDate | 2013-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-0812d5d7867d4e5893ed5e656becf86f2022-12-21T19:41:44ZengMDPI AGPlants2223-77472013-10-012458961410.3390/plants2040589Calcium Signals from the VacuoleGerald SchönknechtThe vacuole is by far the largest intracellular Ca2+ store in most plant cells. Here, the current knowledge about the molecular mechanisms of vacuolar Ca2+ release and Ca2+ uptake is summarized, and how different vacuolar Ca2+ channels and Ca2+ pumps may contribute to Ca2+ signaling in plant cells is discussed. To provide a phylogenetic perspective, the distribution of potential vacuolar Ca2+ transporters is compared for different clades of photosynthetic eukaryotes. There are several candidates for vacuolar Ca2+ channels that could elicit cytosolic [Ca2+] transients. Typical second messengers, such as InsP3 and cADPR, seem to trigger vacuolar Ca2+ release, but the molecular mechanism of this Ca2+ release still awaits elucidation. Some vacuolar Ca2+ channels have been identified on a molecular level, the voltage-dependent SV/TPC1 channel, and recently two cyclic-nucleotide-gated cation channels. However, their function in Ca2+ signaling still has to be demonstrated. Ca2+ pumps in addition to establishing long-term Ca2+ homeostasis can shape cytosolic [Ca2+] transients by limiting their amplitude and duration, and may thus affect Ca2+ signaling.http://www.mdpi.com/2223-7747/2/4/589vacuoleligand-gated Ca2+ channelSV channelcyclic nucleotide-gated channelCa2+:H+ exchangerP-type Ca2+-ATPase |
| spellingShingle | Gerald Schönknecht Calcium Signals from the Vacuole Plants vacuole ligand-gated Ca2+ channel SV channel cyclic nucleotide-gated channel Ca2+:H+ exchanger P-type Ca2+-ATPase |
| title | Calcium Signals from the Vacuole |
| title_full | Calcium Signals from the Vacuole |
| title_fullStr | Calcium Signals from the Vacuole |
| title_full_unstemmed | Calcium Signals from the Vacuole |
| title_short | Calcium Signals from the Vacuole |
| title_sort | calcium signals from the vacuole |
| topic | vacuole ligand-gated Ca2+ channel SV channel cyclic nucleotide-gated channel Ca2+:H+ exchanger P-type Ca2+-ATPase |
| url | http://www.mdpi.com/2223-7747/2/4/589 |
| work_keys_str_mv | AT geraldschonknecht calciumsignalsfromthevacuole |