Imaging Inflammation – From Whole Body Imaging to Cellular Resolution
Imaging techniques have evolved impressively lately, allowing whole new concepts like multimodal imaging, personal medicine, theranostic therapies, and molecular imaging to increase general awareness of possiblities of imaging to medicine field. Here, we have collected the selected (3D) imaging moda...
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-06-01
|
| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.692222/full |
| _version_ | 1818589174200008704 |
|---|---|
| author | Tuula Peñate Medina Jan Philip Kolb Gereon Hüttmann Gereon Hüttmann Robert Huber Oula Peñate Medina Oula Peñate Medina Linh Ha Patricia Ulloa Naomi Larsen Arianna Ferrari Magdalena Rafecas Mark Ellrichmann Mariya S. Pravdivtseva Mariya S. Pravdivtseva Mariia Anikeeva Jana Humbert Jana Humbert Marcus Both Jennifer E. Hundt Jan-Bernd Hövener |
| author_facet | Tuula Peñate Medina Jan Philip Kolb Gereon Hüttmann Gereon Hüttmann Robert Huber Oula Peñate Medina Oula Peñate Medina Linh Ha Patricia Ulloa Naomi Larsen Arianna Ferrari Magdalena Rafecas Mark Ellrichmann Mariya S. Pravdivtseva Mariya S. Pravdivtseva Mariia Anikeeva Jana Humbert Jana Humbert Marcus Both Jennifer E. Hundt Jan-Bernd Hövener |
| author_sort | Tuula Peñate Medina |
| collection | DOAJ |
| description | Imaging techniques have evolved impressively lately, allowing whole new concepts like multimodal imaging, personal medicine, theranostic therapies, and molecular imaging to increase general awareness of possiblities of imaging to medicine field. Here, we have collected the selected (3D) imaging modalities and evaluated the recent findings on preclinical and clinical inflammation imaging. The focus has been on the feasibility of imaging to aid in inflammation precision medicine, and the key challenges and opportunities of the imaging modalities are presented. Some examples of the current usage in clinics/close to clinics have been brought out as an example. This review evaluates the future prospects of the imaging technologies for clinical applications in precision medicine from the pre-clinical development point of view. |
| first_indexed | 2024-12-16T09:36:27Z |
| format | Article |
| id | doaj.art-0816e60bf23c465aa04f3e40d520ffb1 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-16T09:36:27Z |
| publishDate | 2021-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-0816e60bf23c465aa04f3e40d520ffb12022-12-21T22:36:23ZengFrontiers Media S.A.Frontiers in Immunology1664-32242021-06-011210.3389/fimmu.2021.692222692222Imaging Inflammation – From Whole Body Imaging to Cellular ResolutionTuula Peñate Medina0Jan Philip Kolb1Gereon Hüttmann2Gereon Hüttmann3Robert Huber4Oula Peñate Medina5Oula Peñate Medina6Linh Ha7Patricia Ulloa8Naomi Larsen9Arianna Ferrari10Magdalena Rafecas11Mark Ellrichmann12Mariya S. Pravdivtseva13Mariya S. Pravdivtseva14Mariia Anikeeva15Jana Humbert16Jana Humbert17Marcus Both18Jennifer E. Hundt19Jan-Bernd Hövener20Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center, Schleswig-Holstein Kiel University, Kiel, GermanyInstitute of Biomedical Optics, University of Lübeck, Lübeck, GermanyInstitute of Biomedical Optics, University of Lübeck, Lübeck, GermanyAirway Research Center North (ARCN), Member of the German Center of Lung Research (DZL), Gießen, GermanyInstitute of Biomedical Optics, University of Lübeck, Lübeck, GermanySection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center, Schleswig-Holstein Kiel University, Kiel, GermanyInstitute for Experimental Cancer Research (IET), University of Kiel, Kiel, GermanyDepartment of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein Lübeck (UKSH), Lübeck, GermanyDepartment of Radiology and Neuroradiology, University Medical Centers Schleswig-Holstein, Campus Kiel, Kiel, GermanyDepartment of Radiology and Neuroradiology, University Medical Centers Schleswig-Holstein, Campus Kiel, Kiel, GermanySection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center, Schleswig-Holstein Kiel University, Kiel, GermanyInstitute of Medical Engineering (IMT), University of Lübeck, Lübeck, GermanyInterdisciplinary Endoscopy, Medical Department1, University Hospital Schleswig-Holstein, Kiel, GermanySection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center, Schleswig-Holstein Kiel University, Kiel, GermanyDepartment of Radiology and Neuroradiology, University Medical Centers Schleswig-Holstein, Campus Kiel, Kiel, GermanySection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center, Schleswig-Holstein Kiel University, Kiel, GermanySection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center, Schleswig-Holstein Kiel University, Kiel, GermanyDepartment of Radiology and Neuroradiology, University Medical Centers Schleswig-Holstein, Campus Kiel, Kiel, GermanyDepartment of Radiology and Neuroradiology, University Medical Centers Schleswig-Holstein, Campus Kiel, Kiel, GermanyLübeck Institute for Experimental Dermatology (LIED), University of Lübeck, Lübeck, GermanySection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center, Schleswig-Holstein Kiel University, Kiel, GermanyImaging techniques have evolved impressively lately, allowing whole new concepts like multimodal imaging, personal medicine, theranostic therapies, and molecular imaging to increase general awareness of possiblities of imaging to medicine field. Here, we have collected the selected (3D) imaging modalities and evaluated the recent findings on preclinical and clinical inflammation imaging. The focus has been on the feasibility of imaging to aid in inflammation precision medicine, and the key challenges and opportunities of the imaging modalities are presented. Some examples of the current usage in clinics/close to clinics have been brought out as an example. This review evaluates the future prospects of the imaging technologies for clinical applications in precision medicine from the pre-clinical development point of view.https://www.frontiersin.org/articles/10.3389/fimmu.2021.692222/fullMRIPETSPECToptical imagingOptical coherence tomography (OCT)precision medicine |
| spellingShingle | Tuula Peñate Medina Jan Philip Kolb Gereon Hüttmann Gereon Hüttmann Robert Huber Oula Peñate Medina Oula Peñate Medina Linh Ha Patricia Ulloa Naomi Larsen Arianna Ferrari Magdalena Rafecas Mark Ellrichmann Mariya S. Pravdivtseva Mariya S. Pravdivtseva Mariia Anikeeva Jana Humbert Jana Humbert Marcus Both Jennifer E. Hundt Jan-Bernd Hövener Imaging Inflammation – From Whole Body Imaging to Cellular Resolution Frontiers in Immunology MRI PET SPECT optical imaging Optical coherence tomography (OCT) precision medicine |
| title | Imaging Inflammation – From Whole Body Imaging to Cellular Resolution |
| title_full | Imaging Inflammation – From Whole Body Imaging to Cellular Resolution |
| title_fullStr | Imaging Inflammation – From Whole Body Imaging to Cellular Resolution |
| title_full_unstemmed | Imaging Inflammation – From Whole Body Imaging to Cellular Resolution |
| title_short | Imaging Inflammation – From Whole Body Imaging to Cellular Resolution |
| title_sort | imaging inflammation from whole body imaging to cellular resolution |
| topic | MRI PET SPECT optical imaging Optical coherence tomography (OCT) precision medicine |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2021.692222/full |
| work_keys_str_mv | AT tuulapenatemedina imaginginflammationfromwholebodyimagingtocellularresolution AT janphilipkolb imaginginflammationfromwholebodyimagingtocellularresolution AT gereonhuttmann imaginginflammationfromwholebodyimagingtocellularresolution AT gereonhuttmann imaginginflammationfromwholebodyimagingtocellularresolution AT roberthuber imaginginflammationfromwholebodyimagingtocellularresolution AT oulapenatemedina imaginginflammationfromwholebodyimagingtocellularresolution AT oulapenatemedina imaginginflammationfromwholebodyimagingtocellularresolution AT linhha imaginginflammationfromwholebodyimagingtocellularresolution AT patriciaulloa imaginginflammationfromwholebodyimagingtocellularresolution AT naomilarsen imaginginflammationfromwholebodyimagingtocellularresolution AT ariannaferrari imaginginflammationfromwholebodyimagingtocellularresolution AT magdalenarafecas imaginginflammationfromwholebodyimagingtocellularresolution AT markellrichmann imaginginflammationfromwholebodyimagingtocellularresolution AT mariyaspravdivtseva imaginginflammationfromwholebodyimagingtocellularresolution AT mariyaspravdivtseva imaginginflammationfromwholebodyimagingtocellularresolution AT mariiaanikeeva imaginginflammationfromwholebodyimagingtocellularresolution AT janahumbert imaginginflammationfromwholebodyimagingtocellularresolution AT janahumbert imaginginflammationfromwholebodyimagingtocellularresolution AT marcusboth imaginginflammationfromwholebodyimagingtocellularresolution AT jenniferehundt imaginginflammationfromwholebodyimagingtocellularresolution AT janberndhovener imaginginflammationfromwholebodyimagingtocellularresolution |