Joint use of population pharmacokinetics and machine learning for optimizing antiepileptic treatment in pediatric population

Joint use of population pharmacokinetics and machine learning for optimizing antiepileptic treatment in pediatric population

Purpose: Unpredictable drug efficacy and safety of combined antiepileptic therapy is a major challenge during pharmacotherapy decisions in everyday clinical practice. The aim of this study was to describe the pharmacokinetics of valproic acid (VA), lamotrigine (LTG), and levetiracetam (LEV) in a ped...

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Bibliographic Details
Main Authors: Ivana Damnjanović, Nastia Tsyplakova, Nikola Stefanović, Tatjana Tošić, Aleksandra Catić-Đorđević, Vangelis Karalis
Format: Article
Language:English
Published: SAGE Publishing 2023-06-01
Series:Therapeutic Advances in Drug Safety
Online Access:https://doi.org/10.1177/20420986231181337

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