The Effect of Vitamin D and Calcium plus Vitamin D during Pregnancy on Pregnancy and Birth Outcomes: a Randomized Controlled Trial

Introduction: Evidence suggests a high prevalence of calcium and vitamin D deficiencies exists in both pregnant women and babies. Adequate intake of micronutrients has great importance especially during pregnancy and lactation period. Thus, the present study aimed at assessing the effect of vitamin...

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Main Authors: Sakineh Mohammad-Alizadeh-Charandabi, Mojgan Mirghafourvand, Ameneh Mansouri, Moslem Najafi, Farzane Khodabande
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2015-03-01
Series:Journal of Caring Sciences
Subjects:
Online Access:http://journals.tbzmed.ac.ir/JCS/Manuscript/JCS-4-35.pdf
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author Sakineh Mohammad-Alizadeh-Charandabi
Mojgan Mirghafourvand
Ameneh Mansouri
Moslem Najafi
Farzane Khodabande
author_facet Sakineh Mohammad-Alizadeh-Charandabi
Mojgan Mirghafourvand
Ameneh Mansouri
Moslem Najafi
Farzane Khodabande
author_sort Sakineh Mohammad-Alizadeh-Charandabi
collection DOAJ
description Introduction: Evidence suggests a high prevalence of calcium and vitamin D deficiencies exists in both pregnant women and babies. Adequate intake of micronutrients has great importance especially during pregnancy and lactation period. Thus, the present study aimed at assessing the effect of vitamin D and calcium-vitamin D on pregnancy and birth outcomes (including duration of pregnancy, type of delivery and infant anthropometric indicators). Methods: A randomized, controlled, clinical, triple-blind trial conducted on 126 pregnant women referring to Tabriz health centers in 2013-14. Subjects were allocated into three groups using block randomization. Interventional groups received vitamin D, calcium-vitamin D and placebo pills daily for 60 days. ANCOVA and Chi-square tests were used for data analysis. Results: By controlling BMI before and during pregnancy, there were no significant differences between the group in average neonatal weight, height and head circumference, duration of pregnancy, type of delivery and gestational age at the time of delivery. Conclusion: The results show that calcium-vitamin D and vitamin D have no effect on duration of pregnancy, type of delivery and infant anthropometric indicators.
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spelling doaj.art-0818fced5d32451e90f8256edbe4f6d22022-12-22T03:20:33ZengTabriz University of Medical SciencesJournal of Caring Sciences2251-99202251-99202015-03-0141354410.5681/jcs.2015.004The Effect of Vitamin D and Calcium plus Vitamin D during Pregnancy on Pregnancy and Birth Outcomes: a Randomized Controlled TrialSakineh Mohammad-Alizadeh-Charandabi0Mojgan Mirghafourvand1Ameneh Mansouri2Moslem Najafi3Farzane Khodabande4Department of Midwifery, Research Center of Health Effective Social Factors, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Midwifery, Students’ Research Committee, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran Department of Pharmacology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran Department of Midwifery, Students’ Research Committee, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran Introduction: Evidence suggests a high prevalence of calcium and vitamin D deficiencies exists in both pregnant women and babies. Adequate intake of micronutrients has great importance especially during pregnancy and lactation period. Thus, the present study aimed at assessing the effect of vitamin D and calcium-vitamin D on pregnancy and birth outcomes (including duration of pregnancy, type of delivery and infant anthropometric indicators). Methods: A randomized, controlled, clinical, triple-blind trial conducted on 126 pregnant women referring to Tabriz health centers in 2013-14. Subjects were allocated into three groups using block randomization. Interventional groups received vitamin D, calcium-vitamin D and placebo pills daily for 60 days. ANCOVA and Chi-square tests were used for data analysis. Results: By controlling BMI before and during pregnancy, there were no significant differences between the group in average neonatal weight, height and head circumference, duration of pregnancy, type of delivery and gestational age at the time of delivery. Conclusion: The results show that calcium-vitamin D and vitamin D have no effect on duration of pregnancy, type of delivery and infant anthropometric indicators.http://journals.tbzmed.ac.ir/JCS/Manuscript/JCS-4-35.pdfPregnancyVitamin DCalcium
spellingShingle Sakineh Mohammad-Alizadeh-Charandabi
Mojgan Mirghafourvand
Ameneh Mansouri
Moslem Najafi
Farzane Khodabande
The Effect of Vitamin D and Calcium plus Vitamin D during Pregnancy on Pregnancy and Birth Outcomes: a Randomized Controlled Trial
Journal of Caring Sciences
Pregnancy
Vitamin D
Calcium
title The Effect of Vitamin D and Calcium plus Vitamin D during Pregnancy on Pregnancy and Birth Outcomes: a Randomized Controlled Trial
title_full The Effect of Vitamin D and Calcium plus Vitamin D during Pregnancy on Pregnancy and Birth Outcomes: a Randomized Controlled Trial
title_fullStr The Effect of Vitamin D and Calcium plus Vitamin D during Pregnancy on Pregnancy and Birth Outcomes: a Randomized Controlled Trial
title_full_unstemmed The Effect of Vitamin D and Calcium plus Vitamin D during Pregnancy on Pregnancy and Birth Outcomes: a Randomized Controlled Trial
title_short The Effect of Vitamin D and Calcium plus Vitamin D during Pregnancy on Pregnancy and Birth Outcomes: a Randomized Controlled Trial
title_sort effect of vitamin d and calcium plus vitamin d during pregnancy on pregnancy and birth outcomes a randomized controlled trial
topic Pregnancy
Vitamin D
Calcium
url http://journals.tbzmed.ac.ir/JCS/Manuscript/JCS-4-35.pdf
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