Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo

Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo

Abstract Silver nanoparticles (AgNPs) show promise for treatment of aggressive cancers including triple‐negative breast cancer (TNBC) in preclinical cancer models. For clinical development of AgNP‐based therapeutics, it will be necessary to clearly define the specific physicochemical features of the...

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Bibliographic Details
Main Authors: Jessica Swanner, Cale D. Fahrenholtz, Iliana Tenvooren, Brian W. Bernish, James J. Sears, Allison Hooker, Cristina M. Furdui, Elizabeth Alli, Wencheng Li, George L. Donati, Katherine L. Cook, Pierre‐Alexandre Vidi, Ravi Singh
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:FASEB BioAdvances
Subjects:
DNA damage
nanomedicine
redox
toxicity
unfolded protein response
Online Access:https://doi.org/10.1096/fba.2019-00021

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