DNA Double Strand Break and Response Fluorescent Assays: Choices and Interpretation

DNA Double Strand Break and Response Fluorescent Assays: Choices and Interpretation

Accurately characterizing DNA double-stranded breaks (DSBs) and understanding the DNA damage response (DDR) is crucial for assessing cellular genotoxicity, maintaining genomic integrity, and advancing gene editing technologies. Immunofluorescence-based techniques have proven to be invaluable for qua...

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Bibliographic Details
Main Authors:	Jake Atkinson, Eva Bezak, Hien Le, Ivan Kempson
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Series:	International Journal of Molecular Sciences
Subjects:	microscopy non-homologous end joining (NHEJ) homologous-recombination (HR) γH2AX p53 Binding Protein 1 (53BP1) foci
Online Access:	https://www.mdpi.com/1422-0067/25/4/2227

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