Pro-Inflammatory Cytokines Enhanced In Vitro Cytotoxic Activity of <i>Clostridioides difficile</i> Toxin B in Enteric Glial Cells: The Achilles Heel of <i>Clostridioides difficile</i> Infection?

Pro-Inflammatory Cytokines Enhanced In Vitro Cytotoxic Activity of <i>Clostridioides difficile</i> Toxin B in Enteric Glial Cells: The Achilles Heel of <i>Clostridioides difficile</i> Infection?

Bacterial infections are characterized by an inflammatory response, which is essential for infection containment but is also responsible for negative effects on the host. The pathogen itself may have evolved molecular mechanisms to antagonize the antimicrobial effects of an inflammatory response and...

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Bibliographic Details
Main Authors: Katia Fettucciari, Andrea Spaterna, Pierfrancesco Marconi, Gabrio Bassotti
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Clostridioides difficile</i>
<i>Clostridioides difficile</i> toxin B
apoptosis
necrosis
pro-inflammatory cytokines
tumor necrosis factor alpha
Online Access:https://www.mdpi.com/1422-0067/25/2/958

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