Oxidized low density lipoprotein receptor 1 promotes lung metastases of osteosarcomas through regulating the epithelial-mesenchymal transition

Oxidized low density lipoprotein receptor 1 promotes lung metastases of osteosarcomas through regulating the epithelial-mesenchymal transition

Abstract Background Oxidized low density lipoprotein receptor 1 (OLR1), a type II membrane protein, has been identified as receptor for oxidized low-density lipoprotein. The current study firstly provided evidence that OLR1 regulated EMT and thus promoted lung metastases in osteosarcoma (OS). Method...

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Bibliographic Details
Main Authors: Long Jiang, Shanshan Jiang, Wenjie Zhou, Jia Huang, Yongbin Lin, Hao Long, Qingquan Luo
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Translational Medicine
Subjects:
OLR1
Lung metastasis
Osteosarcoma
EMT
Online Access:http://link.springer.com/article/10.1186/s12967-019-2107-9

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