Familial aggregation of phenotypic expression of premature hair hypopigmentation in the craniofacial region
There are many patients who experience premature hypopigmentation of hair, but do not understand the underlying causes and potential dangers associated with them. The causes range from genetic predisposition to environmental influences such as tobacco use. Premature hypopigmentation of the hair shaf...
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| Format: | Article |
| Language: | English |
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University Library System, University of Pittsburgh
2015-04-01
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| Series: | Dentistry 3000 |
| Subjects: | |
| Online Access: | http://dentistry3000.pitt.edu/ojs/index.php/dentistry3000/article/view/31 |
| _version_ | 1828769661138763776 |
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| author | Corey Black |
| author_facet | Corey Black |
| author_sort | Corey Black |
| collection | DOAJ |
| description | There are many patients who experience premature hypopigmentation of hair, but do not understand the underlying causes and potential dangers associated with them. The causes range from genetic predisposition to environmental influences such as tobacco use. Premature hypopigmentation of the hair shaft can also be associated with many syndromes; some which cause dental anomalies. Today, treatment options are limited for patients, although various studies are being done on mice to target the underlying mechanism of action. Understanding the differences between all of the possible causes of this particular phenotype can help clinicians better identify the symptoms, educate patients, and possibly modify treatment to suit the needs of each patient on an individual basis. |
| first_indexed | 2024-12-11T13:52:08Z |
| format | Article |
| id | doaj.art-08219e72a4954ccaa2061ae8c23379ff |
| institution | Directory Open Access Journal |
| issn | 2167-8677 |
| language | English |
| last_indexed | 2024-12-11T13:52:08Z |
| publishDate | 2015-04-01 |
| publisher | University Library System, University of Pittsburgh |
| record_format | Article |
| series | Dentistry 3000 |
| spelling | doaj.art-08219e72a4954ccaa2061ae8c23379ff2022-12-22T01:04:13ZengUniversity Library System, University of PittsburghDentistry 30002167-86772015-04-01312410.5195/d3000.2015.3116Familial aggregation of phenotypic expression of premature hair hypopigmentation in the craniofacial regionCorey Black0University of PittsburghThere are many patients who experience premature hypopigmentation of hair, but do not understand the underlying causes and potential dangers associated with them. The causes range from genetic predisposition to environmental influences such as tobacco use. Premature hypopigmentation of the hair shaft can also be associated with many syndromes; some which cause dental anomalies. Today, treatment options are limited for patients, although various studies are being done on mice to target the underlying mechanism of action. Understanding the differences between all of the possible causes of this particular phenotype can help clinicians better identify the symptoms, educate patients, and possibly modify treatment to suit the needs of each patient on an individual basis.http://dentistry3000.pitt.edu/ojs/index.php/dentistry3000/article/view/31Premature hypopigmentation, gray hair, hair color, male, tobacco, genetic, shaft, follicle, human, adolescent, melanocyte, melanin, stem cells |
| spellingShingle | Corey Black Familial aggregation of phenotypic expression of premature hair hypopigmentation in the craniofacial region Dentistry 3000 Premature hypopigmentation, gray hair, hair color, male, tobacco, genetic, shaft, follicle, human, adolescent, melanocyte, melanin, stem cells |
| title | Familial aggregation of phenotypic expression of premature hair hypopigmentation in the craniofacial region |
| title_full | Familial aggregation of phenotypic expression of premature hair hypopigmentation in the craniofacial region |
| title_fullStr | Familial aggregation of phenotypic expression of premature hair hypopigmentation in the craniofacial region |
| title_full_unstemmed | Familial aggregation of phenotypic expression of premature hair hypopigmentation in the craniofacial region |
| title_short | Familial aggregation of phenotypic expression of premature hair hypopigmentation in the craniofacial region |
| title_sort | familial aggregation of phenotypic expression of premature hair hypopigmentation in the craniofacial region |
| topic | Premature hypopigmentation, gray hair, hair color, male, tobacco, genetic, shaft, follicle, human, adolescent, melanocyte, melanin, stem cells |
| url | http://dentistry3000.pitt.edu/ojs/index.php/dentistry3000/article/view/31 |
| work_keys_str_mv | AT coreyblack familialaggregationofphenotypicexpressionofprematurehairhypopigmentationinthecraniofacialregion |