Adverse Effects of DPT Vaccine in Children below 7 Years of Age in Rural and Urban Areas of Kohgiloye and Boyerahmad Province In 1385
Introduction & Objective: Vaccination is an important and precious intervention which can protect individuals and community against vaccine preventable diseases with low cost. Although vaccines in use including DPT are very effective but there is no vaccine without adverse events. The DPT advers...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Yasuj University Of Medical Sciences
2008-07-01
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| Series: | Armaghane Danesh Bimonthly Journal |
| Subjects: | |
| Online Access: | http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-39-31&slc_lang=en&sid=1 |
| Summary: | Introduction & Objective: Vaccination is an important and
precious intervention which can protect individuals and community
against vaccine preventable diseases with low cost. Although
vaccines in use including DPT are very effective but there is no
vaccine without adverse events. The DPT adverse events can be
classified as vaccine reaction, injection reaction, coincidental
events and program error. The aims of this study were to
investigate the adverse events of DPT and providing measures for
improvement of existing surveillance and reporting system.
Materials & Methods: in this cross sectional study a total number
of 2000 children who were vaccinated with DPT were followed for a
4 month periods from the beginning of June to the end of
September for adverse events. Sampling was done by clustering
methods in 20% of rural and urban health centers which were
randomly selected. A structural questionnaire was completed for
each subject along with interview and physical exam. Data were
analyzed using SPSS software version 11.5
Results: Systemic reactions including loss of appetite was seen in
4.9%, fatigue in 3%, pallor in 1.8%, crying for more than 3 hours in
1.6% and vomiting in 1.5% of vaccinated children. local reactions
was seen in 56% of cases which were including: redness in the
injection site (13.5%), swelling without redness (12.2%), swelling
with redness (6.2%). Vaccine reaction (fever as the most) was
noted in 45% of cases, program error in 7.6% of cases, injection
reaction in 3% of children and coincidental in 1.2% of children.
Conclusion: the most common adverse event following DPT
vaccine was due to vaccine reaction. Injection site had the most
quotas in presenting the vaccine reaction. We suggest changing of
the DPT injection site from deltoid to upper outer part of thigh.
Injection reaction can also be due to first experience of the young
children in their first vaccination schedule |
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| ISSN: | 1728-6506 1728-6514 |