Clinicians’ and Researchers’ Views on Precision Medicine in Chronic Inflammation: Practices, Benefits and Challenges
(1) Background: Due to the high burden of diseases with chronic inflammation as an underlying condition, great expectations are placed in the development of precision medicine (PM). Our research explores the benefits and possible risks of this development from the perspective of clinicians and resea...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Journal of Personalized Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4426/12/4/574 |
| _version_ | 1797410533728583680 |
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| author | Anke Erdmann Christoph Rehmann-Sutter Claudia Bozzaro |
| author_facet | Anke Erdmann Christoph Rehmann-Sutter Claudia Bozzaro |
| author_sort | Anke Erdmann |
| collection | DOAJ |
| description | (1) Background: Due to the high burden of diseases with chronic inflammation as an underlying condition, great expectations are placed in the development of precision medicine (PM). Our research explores the benefits and possible risks of this development from the perspective of clinicians and researchers in the field. We have asked these professionals about the current state of their research and their expectations, concerns, values and attitudes regarding PM. (2) Methods: Following a grounded theory approach, we conducted qualitative interviews with 17 clinicians and researchers. For respondent validation, we discussed the findings with the participants in a validation workshop. (3) Results: Professionals expect multiple benefits from PM in chronic inflammation. They provided their concepts of professionals’ and patients’ work in the development of PM in chronic inflammatory diseases. Ethical, process-related and economic challenges were raised regarding the lack of integration of data from minority groups, the risk of data misuse and discrimination, the potential risk of no therapy being available for small strata, the lack of professional support and political measures in developing a healthy lifestyle, the problem of difficult access to the inflammation clinic for some populations and the difficulty of financing PM for all. (4) Conclusions: In the further research, development and implementation of PM, these ethical challenges need to be adequately addressed. |
| first_indexed | 2024-03-09T04:30:24Z |
| format | Article |
| id | doaj.art-082cd163625c43bda9c994bd7f89336e |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T04:30:24Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-082cd163625c43bda9c994bd7f89336e2023-12-03T13:35:16ZengMDPI AGJournal of Personalized Medicine2075-44262022-04-0112457410.3390/jpm12040574Clinicians’ and Researchers’ Views on Precision Medicine in Chronic Inflammation: Practices, Benefits and ChallengesAnke Erdmann0Christoph Rehmann-Sutter1Claudia Bozzaro2Institute for Experimental Medicine, Medical Ethics Working Group, Kiel University, 24105 Kiel, GermanyInstitute for History of Medicine and Science Studies, University of Lübeck, 23552 Lübeck, GermanyInstitute for Experimental Medicine, Medical Ethics Working Group, Kiel University, 24105 Kiel, Germany(1) Background: Due to the high burden of diseases with chronic inflammation as an underlying condition, great expectations are placed in the development of precision medicine (PM). Our research explores the benefits and possible risks of this development from the perspective of clinicians and researchers in the field. We have asked these professionals about the current state of their research and their expectations, concerns, values and attitudes regarding PM. (2) Methods: Following a grounded theory approach, we conducted qualitative interviews with 17 clinicians and researchers. For respondent validation, we discussed the findings with the participants in a validation workshop. (3) Results: Professionals expect multiple benefits from PM in chronic inflammation. They provided their concepts of professionals’ and patients’ work in the development of PM in chronic inflammatory diseases. Ethical, process-related and economic challenges were raised regarding the lack of integration of data from minority groups, the risk of data misuse and discrimination, the potential risk of no therapy being available for small strata, the lack of professional support and political measures in developing a healthy lifestyle, the problem of difficult access to the inflammation clinic for some populations and the difficulty of financing PM for all. (4) Conclusions: In the further research, development and implementation of PM, these ethical challenges need to be adequately addressed.https://www.mdpi.com/2075-4426/12/4/574precision medicinepersonalized medicinejusticedata misusediscriminationethnic group |
| spellingShingle | Anke Erdmann Christoph Rehmann-Sutter Claudia Bozzaro Clinicians’ and Researchers’ Views on Precision Medicine in Chronic Inflammation: Practices, Benefits and Challenges Journal of Personalized Medicine precision medicine personalized medicine justice data misuse discrimination ethnic group |
| title | Clinicians’ and Researchers’ Views on Precision Medicine in Chronic Inflammation: Practices, Benefits and Challenges |
| title_full | Clinicians’ and Researchers’ Views on Precision Medicine in Chronic Inflammation: Practices, Benefits and Challenges |
| title_fullStr | Clinicians’ and Researchers’ Views on Precision Medicine in Chronic Inflammation: Practices, Benefits and Challenges |
| title_full_unstemmed | Clinicians’ and Researchers’ Views on Precision Medicine in Chronic Inflammation: Practices, Benefits and Challenges |
| title_short | Clinicians’ and Researchers’ Views on Precision Medicine in Chronic Inflammation: Practices, Benefits and Challenges |
| title_sort | clinicians and researchers views on precision medicine in chronic inflammation practices benefits and challenges |
| topic | precision medicine personalized medicine justice data misuse discrimination ethnic group |
| url | https://www.mdpi.com/2075-4426/12/4/574 |
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