Iodine-doped TiO2 nanotube coatings: a technique for enhancing the antimicrobial properties of titanium surfaces against Staphylococcus aureus
Abstract Background Implant-related infections are a challenging complication of orthopedic surgery, primarily due to the formation of bacterial biofilms on the implant surface. An antibacterial coating for titanium implants was developed to provide novel insights into the prevention and treatment o...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | Journal of Orthopaedic Surgery and Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13018-023-04354-8 |
| _version_ | 1797630076603334656 |
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| author | Xiu Yang Neng-Fu Chen Xiao-Li Huang Shun Lin Qing-Quan Chen Wan-Ming Wang Jin-Shui Chen |
| author_facet | Xiu Yang Neng-Fu Chen Xiao-Li Huang Shun Lin Qing-Quan Chen Wan-Ming Wang Jin-Shui Chen |
| author_sort | Xiu Yang |
| collection | DOAJ |
| description | Abstract Background Implant-related infections are a challenging complication of orthopedic surgery, primarily due to the formation of bacterial biofilms on the implant surface. An antibacterial coating for titanium implants was developed to provide novel insights into the prevention and treatment of implant-related infections. Methods Titanium plates were coated with TiO2 nanotubes by anodization, and iodine was doped onto the coating via electrophoretic deposition. The obtained plates were characterized using a range of analytical techniques. Subsequently, Staphylococcus aureus was inoculated onto the surfaces of untreated titanium plates (control group), TiO2-nanocoated titanium plates (TiO2 group), and iodine-doped TiO2-nanocoated titanium plates (I-TiO2 group) to compare their antibacterial properties. Results Twenty-four hour in vitro antimicrobial activity test of the I-TiO2 group against Staphylococcus aureus was superior to those of the other groups, and this difference was statistically significant (P < 0.05). Conclusions This coating technology provides a new theoretical basis for the development of anti-infective implants against Staphylococcus aureus in orthopedics. |
| first_indexed | 2024-03-11T11:01:49Z |
| format | Article |
| id | doaj.art-082e735bbdc64185839eead0577262c8 |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-03-11T11:01:49Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-082e735bbdc64185839eead0577262c82023-11-12T12:24:30ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2023-11-011811910.1186/s13018-023-04354-8Iodine-doped TiO2 nanotube coatings: a technique for enhancing the antimicrobial properties of titanium surfaces against Staphylococcus aureusXiu Yang0Neng-Fu Chen1Xiao-Li Huang2Shun Lin3Qing-Quan Chen4Wan-Ming Wang5Jin-Shui Chen6Fuzong Clinical Medical College of Fujian Medical UniversityFuzhou Second HospitalFujian Medical UniversityFuzong Clinical Medical College of Fujian Medical UniversityFuzong Clinical Medical College of Fujian Medical UniversityFuzong Clinical Medical College of Fujian Medical UniversityFuzong Clinical Medical College of Fujian Medical UniversityAbstract Background Implant-related infections are a challenging complication of orthopedic surgery, primarily due to the formation of bacterial biofilms on the implant surface. An antibacterial coating for titanium implants was developed to provide novel insights into the prevention and treatment of implant-related infections. Methods Titanium plates were coated with TiO2 nanotubes by anodization, and iodine was doped onto the coating via electrophoretic deposition. The obtained plates were characterized using a range of analytical techniques. Subsequently, Staphylococcus aureus was inoculated onto the surfaces of untreated titanium plates (control group), TiO2-nanocoated titanium plates (TiO2 group), and iodine-doped TiO2-nanocoated titanium plates (I-TiO2 group) to compare their antibacterial properties. Results Twenty-four hour in vitro antimicrobial activity test of the I-TiO2 group against Staphylococcus aureus was superior to those of the other groups, and this difference was statistically significant (P < 0.05). Conclusions This coating technology provides a new theoretical basis for the development of anti-infective implants against Staphylococcus aureus in orthopedics.https://doi.org/10.1186/s13018-023-04354-8Antibacterial coatingTitanium plateIodineTiO2 nanotubes |
| spellingShingle | Xiu Yang Neng-Fu Chen Xiao-Li Huang Shun Lin Qing-Quan Chen Wan-Ming Wang Jin-Shui Chen Iodine-doped TiO2 nanotube coatings: a technique for enhancing the antimicrobial properties of titanium surfaces against Staphylococcus aureus Journal of Orthopaedic Surgery and Research Antibacterial coating Titanium plate Iodine TiO2 nanotubes |
| title | Iodine-doped TiO2 nanotube coatings: a technique for enhancing the antimicrobial properties of titanium surfaces against Staphylococcus aureus |
| title_full | Iodine-doped TiO2 nanotube coatings: a technique for enhancing the antimicrobial properties of titanium surfaces against Staphylococcus aureus |
| title_fullStr | Iodine-doped TiO2 nanotube coatings: a technique for enhancing the antimicrobial properties of titanium surfaces against Staphylococcus aureus |
| title_full_unstemmed | Iodine-doped TiO2 nanotube coatings: a technique for enhancing the antimicrobial properties of titanium surfaces against Staphylococcus aureus |
| title_short | Iodine-doped TiO2 nanotube coatings: a technique for enhancing the antimicrobial properties of titanium surfaces against Staphylococcus aureus |
| title_sort | iodine doped tio2 nanotube coatings a technique for enhancing the antimicrobial properties of titanium surfaces against staphylococcus aureus |
| topic | Antibacterial coating Titanium plate Iodine TiO2 nanotubes |
| url | https://doi.org/10.1186/s13018-023-04354-8 |
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