Ring finger protein 180 suppresses cell proliferation and energy metabolism of non-small cell lung cancer through downregulating C-myc

Ring finger protein 180 suppresses cell proliferation and energy metabolism of non-small cell lung cancer through downregulating C-myc

Abstract Background Non-small cell lung cancer (NSCLC) causes numerous deaths worldwide. however, biomarkers for NSCLC prognosis are scarce for its heterogeneity. Proteins containing the RING finger domain RING finger protein 180 (RNF180) is a key mediator for ubiquitination, which controls cell cyc...

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Bibliographic Details
Main Authors: Yi Ding, Yi Lu, Xinjie Xie, Lei Cao, Shiying Zheng
Format: Article
Language:English
Published: BMC 2022-05-01
Series:World Journal of Surgical Oncology
Subjects:
Non-small cell lung cancer
RING finger protein 180
C-myc
Cell proliferation
Glycolysis
Ubiquitination
Online Access:https://doi.org/10.1186/s12957-022-02599-x

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