High Dietary Intake of Vegetable Protein Is Associated With Lower Prevalence of Renal Function Impairment: Results of the Dutch DIALECT-1 Cohort
Introduction: Dietary protein intake may influence development of renal function impairment in diabetes mellitus type 2 (T2DM). We assessed the association between sources of protein and prevalence of renal function impairment. Methods: Cross-sectional analyses were performed in baseline data of 420...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-05-01
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| Series: | Kidney International Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468024919300701 |
| _version_ | 1811291483562573824 |
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| author | Milou M. Oosterwijk Sabita S. Soedamah-Muthu Johanna M. Geleijnse Stephan J.L. Bakker Gerjan Navis S. Heleen Binnenmars Christina M. Gant Gozewijn D. Laverman |
| author_facet | Milou M. Oosterwijk Sabita S. Soedamah-Muthu Johanna M. Geleijnse Stephan J.L. Bakker Gerjan Navis S. Heleen Binnenmars Christina M. Gant Gozewijn D. Laverman |
| author_sort | Milou M. Oosterwijk |
| collection | DOAJ |
| description | Introduction: Dietary protein intake may influence development of renal function impairment in diabetes mellitus type 2 (T2DM). We assessed the association between sources of protein and prevalence of renal function impairment. Methods: Cross-sectional analyses were performed in baseline data of 420 patients of the DIAbetes and LifEstyle Cohort Twente-1 (DIALECT-1) study. Protein intake was assessed using a Food Frequency Questionnaire, modified for accurate assessment of protein intake, including types and sources of protein. Renal function impairment was defined as estimated glomerular filtration rate (eGFR) <60 ml/min per 1.73 m2 (Chronic Kidney Disease Epidemiology Collaboration formula). Results: Among 420 patients with T2DM, 99 renal function impairment cases were identified. Multivariate Cox proportional hazard models were used and adjusted for the main lifestyle and dietary factors. The prevalence ratios in the fully adjusted model were 1 (reference), 0.74 (95% confidence interval [CI]: 0.44–1.27; P = 0.28) and 0.47 (95% CI: 0.23–0.98; P = 0.04) according to increasing tertiles of vegetable protein intake. For animal protein intake the prevalence ratios were 1 (reference), 1.10 (95% CI: 0.64–1.88; P = 0.74) and 1.06 (95% CI: 0.56–1.99; P = 0.87) according to increasing tertiles of intake. Theoretical replacement models showed that replacing 3 energy percent from animal protein by vegetable protein lowered the prevalence ratio for the association with renal function impairment to 0.20 (95% CI: 0.06–0.63; P = 0.01). Conclusion: In conclusion, we found that higher intake of vegetable protein was associated with a lower prevalence of renal function impairment, and theoretical replacement of animal protein with vegetable protein was inversely associated with renal function impairment among patients with T2DM. Keywords: diabetes mellitus type 2, diet, kidney function, lifestyle |
| first_indexed | 2024-04-13T04:30:05Z |
| format | Article |
| id | doaj.art-083a6aac07eb420db7b1b26b11dfbdba |
| institution | Directory Open Access Journal |
| issn | 2468-0249 |
| language | English |
| last_indexed | 2024-04-13T04:30:05Z |
| publishDate | 2019-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Kidney International Reports |
| spelling | doaj.art-083a6aac07eb420db7b1b26b11dfbdba2022-12-22T03:02:20ZengElsevierKidney International Reports2468-02492019-05-0145710719High Dietary Intake of Vegetable Protein Is Associated With Lower Prevalence of Renal Function Impairment: Results of the Dutch DIALECT-1 CohortMilou M. Oosterwijk0Sabita S. Soedamah-Muthu1Johanna M. Geleijnse2Stephan J.L. Bakker3Gerjan Navis4S. Heleen Binnenmars5Christina M. Gant6Gozewijn D. Laverman7Department of Internal Medicine/Nephrology, Ziekenhuis Groep Twente, Almelo, the Netherlands; Division of Human Nutrition, Wageningen University, Wageningen, the NetherlandsCenter of Research on Psychological and Somatic Disorders (CoRPS), Department of Medical and Clinical Psychology, Tilburg University, Tilburg, the Netherlands; Institute for Food, Nutrition and Health, University of Reading, Reading, UKDivision of Human Nutrition, Wageningen University, Wageningen, the NetherlandsDepartment of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the NetherlandsDepartment of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the NetherlandsDepartment of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the NetherlandsDepartment of Internal Medicine/Nephrology, Ziekenhuis Groep Twente, Almelo, the Netherlands; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the NetherlandsDepartment of Internal Medicine/Nephrology, Ziekenhuis Groep Twente, Almelo, the Netherlands; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Correspondence: Gozewijn D. Laverman, Ziekenhuis Groep Twente, Department of Internal Medicine/Nephrology, Zilvermeeuw 1, Almelo 7609, the Netherlands.Introduction: Dietary protein intake may influence development of renal function impairment in diabetes mellitus type 2 (T2DM). We assessed the association between sources of protein and prevalence of renal function impairment. Methods: Cross-sectional analyses were performed in baseline data of 420 patients of the DIAbetes and LifEstyle Cohort Twente-1 (DIALECT-1) study. Protein intake was assessed using a Food Frequency Questionnaire, modified for accurate assessment of protein intake, including types and sources of protein. Renal function impairment was defined as estimated glomerular filtration rate (eGFR) <60 ml/min per 1.73 m2 (Chronic Kidney Disease Epidemiology Collaboration formula). Results: Among 420 patients with T2DM, 99 renal function impairment cases were identified. Multivariate Cox proportional hazard models were used and adjusted for the main lifestyle and dietary factors. The prevalence ratios in the fully adjusted model were 1 (reference), 0.74 (95% confidence interval [CI]: 0.44–1.27; P = 0.28) and 0.47 (95% CI: 0.23–0.98; P = 0.04) according to increasing tertiles of vegetable protein intake. For animal protein intake the prevalence ratios were 1 (reference), 1.10 (95% CI: 0.64–1.88; P = 0.74) and 1.06 (95% CI: 0.56–1.99; P = 0.87) according to increasing tertiles of intake. Theoretical replacement models showed that replacing 3 energy percent from animal protein by vegetable protein lowered the prevalence ratio for the association with renal function impairment to 0.20 (95% CI: 0.06–0.63; P = 0.01). Conclusion: In conclusion, we found that higher intake of vegetable protein was associated with a lower prevalence of renal function impairment, and theoretical replacement of animal protein with vegetable protein was inversely associated with renal function impairment among patients with T2DM. Keywords: diabetes mellitus type 2, diet, kidney function, lifestylehttp://www.sciencedirect.com/science/article/pii/S2468024919300701 |
| spellingShingle | Milou M. Oosterwijk Sabita S. Soedamah-Muthu Johanna M. Geleijnse Stephan J.L. Bakker Gerjan Navis S. Heleen Binnenmars Christina M. Gant Gozewijn D. Laverman High Dietary Intake of Vegetable Protein Is Associated With Lower Prevalence of Renal Function Impairment: Results of the Dutch DIALECT-1 Cohort Kidney International Reports |
| title | High Dietary Intake of Vegetable Protein Is Associated With Lower Prevalence of Renal Function Impairment: Results of the Dutch DIALECT-1 Cohort |
| title_full | High Dietary Intake of Vegetable Protein Is Associated With Lower Prevalence of Renal Function Impairment: Results of the Dutch DIALECT-1 Cohort |
| title_fullStr | High Dietary Intake of Vegetable Protein Is Associated With Lower Prevalence of Renal Function Impairment: Results of the Dutch DIALECT-1 Cohort |
| title_full_unstemmed | High Dietary Intake of Vegetable Protein Is Associated With Lower Prevalence of Renal Function Impairment: Results of the Dutch DIALECT-1 Cohort |
| title_short | High Dietary Intake of Vegetable Protein Is Associated With Lower Prevalence of Renal Function Impairment: Results of the Dutch DIALECT-1 Cohort |
| title_sort | high dietary intake of vegetable protein is associated with lower prevalence of renal function impairment results of the dutch dialect 1 cohort |
| url | http://www.sciencedirect.com/science/article/pii/S2468024919300701 |
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