Thrombolysis in acute ischemic stroke: where and when?

The therapy of acute ischemic stroke remains an open challenge for the clinicians and is closely connected to the ready acknowledgment of symptoms, to the promptness of the instrumental diagnosis and consequently to the rapidity of the pharmacological intervention. Although several studies have vali...

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Main Authors: Giuseppe Micieli, Simona Marcheselli, Stefano Ottolini, Salvatore Badalamenti
Format: Article
Language:English
Published: PAGEPress Publications 2007-12-01
Series:Emergency Care Journal
Online Access:http://www.pagepressjournals.org/index.php/ecj/article/view/1231
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author Giuseppe Micieli
Simona Marcheselli
Stefano Ottolini
Salvatore Badalamenti
author_facet Giuseppe Micieli
Simona Marcheselli
Stefano Ottolini
Salvatore Badalamenti
author_sort Giuseppe Micieli
collection DOAJ
description The therapy of acute ischemic stroke remains an open challenge for the clinicians and is closely connected to the ready acknowledgment of symptoms, to the promptness of the instrumental diagnosis and consequently to the rapidity of the pharmacological intervention. Although several studies have validated the effectiveness and the safety profileof the intravenous fibrinolytic treatment, the number of patients who benefit of such therapeutic opportunity is still too little. This data is partially due to the delay within patients arrive to the hospital and to the doubts of the physicians on the possible collateral effects, but it is also related to logistic and organizational-managerial problematic of the patient with acute stroke.These last ones mainly derive from the deficiency on the national territory of dedicated structures (Stroke Unit), from the absence of operative connections between the 118-service and the Stroke Unit, from the delay of the neurologist calling in the emergency room that does not allow an adapted diagnostic evaluation of the ischemic event. The spread of the intravenous fibrinolysis must therefore necessarily pass through the creation of participation protocols between hospitals with stroke unit and primary aid, and between department of emergency/ urgency and staff of the stroke unit also previewing the creation of professional figures like those of the urgency neurologist that could have the full right of the management and the treatment of cerebral ischemic pathology.
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spelling doaj.art-083cf2ac1691433da0810231367dce492022-12-22T00:33:58ZengPAGEPress PublicationsEmergency Care Journal1826-98262007-12-0136182310.4081/ecj.2007.6.18758Thrombolysis in acute ischemic stroke: where and when?Giuseppe Micieli0Simona Marcheselli1Stefano Ottolini2Salvatore Badalamenti3Dipartimento d’Urgenza, IRCCS Istituto Clinico Humanitas, Rozzano (Milano)Dipartimento d’Urgenza, IRCCS Istituto Clinico Humanitas, Rozzano (Milano)Dipartimento d’Urgenza, IRCCS Istituto Clinico Humanitas, Rozzano (Milano)Dipartimento d’Urgenza, IRCCS Istituto Clinico Humanitas, Rozzano (Milano)The therapy of acute ischemic stroke remains an open challenge for the clinicians and is closely connected to the ready acknowledgment of symptoms, to the promptness of the instrumental diagnosis and consequently to the rapidity of the pharmacological intervention. Although several studies have validated the effectiveness and the safety profileof the intravenous fibrinolytic treatment, the number of patients who benefit of such therapeutic opportunity is still too little. This data is partially due to the delay within patients arrive to the hospital and to the doubts of the physicians on the possible collateral effects, but it is also related to logistic and organizational-managerial problematic of the patient with acute stroke.These last ones mainly derive from the deficiency on the national territory of dedicated structures (Stroke Unit), from the absence of operative connections between the 118-service and the Stroke Unit, from the delay of the neurologist calling in the emergency room that does not allow an adapted diagnostic evaluation of the ischemic event. The spread of the intravenous fibrinolysis must therefore necessarily pass through the creation of participation protocols between hospitals with stroke unit and primary aid, and between department of emergency/ urgency and staff of the stroke unit also previewing the creation of professional figures like those of the urgency neurologist that could have the full right of the management and the treatment of cerebral ischemic pathology.http://www.pagepressjournals.org/index.php/ecj/article/view/1231
spellingShingle Giuseppe Micieli
Simona Marcheselli
Stefano Ottolini
Salvatore Badalamenti
Thrombolysis in acute ischemic stroke: where and when?
Emergency Care Journal
title Thrombolysis in acute ischemic stroke: where and when?
title_full Thrombolysis in acute ischemic stroke: where and when?
title_fullStr Thrombolysis in acute ischemic stroke: where and when?
title_full_unstemmed Thrombolysis in acute ischemic stroke: where and when?
title_short Thrombolysis in acute ischemic stroke: where and when?
title_sort thrombolysis in acute ischemic stroke where and when
url http://www.pagepressjournals.org/index.php/ecj/article/view/1231
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AT simonamarcheselli thrombolysisinacuteischemicstrokewhereandwhen
AT stefanoottolini thrombolysisinacuteischemicstrokewhereandwhen
AT salvatorebadalamenti thrombolysisinacuteischemicstrokewhereandwhen