Potential Role of Probiotics in Mechanism of Intestinal Immunity
Probiotics are nonpathogenic bacteria exert a constructive influence on health or physiology of the host. Effect of probiotics in the intestinal defense against variety of diseases is well known. The probiotics are involved in the mechanism of intestinal defense, support as antagonist against pathog...
| Main Author: | |
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| Format: | Article |
| Language: | English |
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University of Agriculture, Faisalabad
2012-06-01
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| Series: | Pakistan Veterinary Journal |
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| Online Access: | http://pvj.com.pk/pdf-files/32_3/303-308.pdf |
| _version_ | 1818481531372437504 |
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| author | Imran Rashid Rajput and Wei Fen Li* |
| author_facet | Imran Rashid Rajput and Wei Fen Li* |
| author_sort | Imran Rashid Rajput and Wei Fen Li* |
| collection | DOAJ |
| description | Probiotics are nonpathogenic bacteria exert a constructive influence on health or physiology of the host. Effect of probiotics in the intestinal defense against variety of diseases is well known. The probiotics are involved in the mechanism of intestinal defense, support as antagonist against pathogens, improve intestinal epithelial layer and boost the innate as well as adaptive immunity. However these responses are also exerted by intestinal components. The intestinal components as well as probiotics play a reciprocal role to enhance the immune response of the individual. The possibilities of mechanism of action include the stimulation of epithelial cells, activation of dendritic cells via toll-like receptors (TLRs), conversely produce cytokines. These observations reviewed together advocate that specific immunomodulatory properties of probiotic bacteria should be focusing on mechanism of action via antigen presenting cells (APC). |
| first_indexed | 2024-12-10T11:36:14Z |
| format | Article |
| id | doaj.art-083d3be5f68447af9217f19ee7bdae26 |
| institution | Directory Open Access Journal |
| issn | 0253-8318 |
| language | English |
| last_indexed | 2024-12-10T11:36:14Z |
| publishDate | 2012-06-01 |
| publisher | University of Agriculture, Faisalabad |
| record_format | Article |
| series | Pakistan Veterinary Journal |
| spelling | doaj.art-083d3be5f68447af9217f19ee7bdae262022-12-22T01:50:25ZengUniversity of Agriculture, FaisalabadPakistan Veterinary Journal0253-83182012-06-01323303308Potential Role of Probiotics in Mechanism of Intestinal ImmunityImran Rashid Rajput and Wei Fen Li*Probiotics are nonpathogenic bacteria exert a constructive influence on health or physiology of the host. Effect of probiotics in the intestinal defense against variety of diseases is well known. The probiotics are involved in the mechanism of intestinal defense, support as antagonist against pathogens, improve intestinal epithelial layer and boost the innate as well as adaptive immunity. However these responses are also exerted by intestinal components. The intestinal components as well as probiotics play a reciprocal role to enhance the immune response of the individual. The possibilities of mechanism of action include the stimulation of epithelial cells, activation of dendritic cells via toll-like receptors (TLRs), conversely produce cytokines. These observations reviewed together advocate that specific immunomodulatory properties of probiotic bacteria should be focusing on mechanism of action via antigen presenting cells (APC).http://pvj.com.pk/pdf-files/32_3/303-308.pdfImmunityMechanismProbiotics |
| spellingShingle | Imran Rashid Rajput and Wei Fen Li* Potential Role of Probiotics in Mechanism of Intestinal Immunity Pakistan Veterinary Journal Immunity Mechanism Probiotics |
| title | Potential Role of Probiotics in Mechanism of Intestinal Immunity |
| title_full | Potential Role of Probiotics in Mechanism of Intestinal Immunity |
| title_fullStr | Potential Role of Probiotics in Mechanism of Intestinal Immunity |
| title_full_unstemmed | Potential Role of Probiotics in Mechanism of Intestinal Immunity |
| title_short | Potential Role of Probiotics in Mechanism of Intestinal Immunity |
| title_sort | potential role of probiotics in mechanism of intestinal immunity |
| topic | Immunity Mechanism Probiotics |
| url | http://pvj.com.pk/pdf-files/32_3/303-308.pdf |
| work_keys_str_mv | AT imranrashidrajputandweifenli potentialroleofprobioticsinmechanismofintestinalimmunity |