What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original Research
Objectives-background: Postoperative cognitive dysfunction (POCD) involves decline in several cognitive domains after surgery and is particularly common after cardiac surgery, while also common among other types of surgery. Given the potential effects of such cognitive dysfunction on the quality of...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-02-01
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| Series: | Neuroscience Insights |
| Online Access: | https://doi.org/10.1177/26331055231220906 |
| _version_ | 1797316498857918464 |
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| author | Kalliopi Megari Evanthia Thomaidou Georgios A. Kougioumtzis Maria Theodoratou Dimitra Katsarou Eleni Karlafti Matthaios Didaggelos Daniel Paramythiotis Eleni Argyriadou |
| author_facet | Kalliopi Megari Evanthia Thomaidou Georgios A. Kougioumtzis Maria Theodoratou Dimitra Katsarou Eleni Karlafti Matthaios Didaggelos Daniel Paramythiotis Eleni Argyriadou |
| author_sort | Kalliopi Megari |
| collection | DOAJ |
| description | Objectives-background: Postoperative cognitive dysfunction (POCD) involves decline in several cognitive domains after surgery and is particularly common after cardiac surgery, while also common among other types of surgery. Given the potential effects of such cognitive dysfunction on the quality of life, it is important to study it in multiple populations in order to limit its occurrence. Study design: We present the long-term neuropsychological outcome of 200 patients, 100 of whom had orthopedic surgery and 100 oncological surgery. Methods: We administered a series of neuropsychological tests assessing attention, complex scanning, verbal working memory, executive functioning, short-term and long-term memory, and visuospatial perception before surgery, prior to discharge, at 3-month follow-up and 6 years after surgery. We compared the performance of these patients to normative datasets. Results: Despite equivalent levels of pre-surgery performance between patients, oncology patients exceeded their preoperative neurocognitive levels, suggesting less postoperative cognitive dysfunction in orthopedic patients overall, in all neuropsychological domains at a 6-year follow-up, except short-term retention. In contrast, orthopedic patients showed no improvement, and, instead, showed some cognitive decline, which remained consistent over time. Conclusions: Our findings highlight the critical role of the type of surgery utilized in the development of POCD and have implications for clinical management and patients’ quality of life in the very long term. Health policy professionals should be aware that patients’ low POCD may persist in the long term, and this is useful from a clinician’s point of view. |
| first_indexed | 2024-03-08T03:20:14Z |
| format | Article |
| id | doaj.art-083df82ec8514cecae2cd85e28ede5b9 |
| institution | Directory Open Access Journal |
| issn | 2633-1055 |
| language | English |
| last_indexed | 2024-03-08T03:20:14Z |
| publishDate | 2024-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Neuroscience Insights |
| spelling | doaj.art-083df82ec8514cecae2cd85e28ede5b92024-02-12T10:03:23ZengSAGE PublishingNeuroscience Insights2633-10552024-02-011910.1177/26331055231220906What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original ResearchKalliopi Megari0Evanthia Thomaidou1Georgios A. Kougioumtzis2Maria Theodoratou3Dimitra Katsarou4Eleni Karlafti5Matthaios Didaggelos6Daniel Paramythiotis7Eleni Argyriadou8School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, GreeceDepartment of Anaesthesiology and Intensive Care Unit, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, GreeceDepartment of Turkish Studies and Modern Asian Studies, Faculty of Economic and Political Sciences, National and Kapodistrian University of Athens, GreeceDepartment of Social Sciences, Hellenic Open University, Patras, GreeceDepartment of Preschool Education Sciences and Educational Design, Faculty of Humanities, University of the Aegean, Mytilene, GreeceEmergency Department, AHEPA University General Hospital, Aristotle University of Thessaloniki, Greece1st Cardiology Department, AHEPA University General Hospital, Aristotle University of Thessaloniki, GreeceFirst Propaedeutic Department of Surgery, AHEPA University General Hospital, Aristotle University of Thessaloniki, GreeceDepartment of Anaesthesiology and Intensive Care Unit, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, GreeceObjectives-background: Postoperative cognitive dysfunction (POCD) involves decline in several cognitive domains after surgery and is particularly common after cardiac surgery, while also common among other types of surgery. Given the potential effects of such cognitive dysfunction on the quality of life, it is important to study it in multiple populations in order to limit its occurrence. Study design: We present the long-term neuropsychological outcome of 200 patients, 100 of whom had orthopedic surgery and 100 oncological surgery. Methods: We administered a series of neuropsychological tests assessing attention, complex scanning, verbal working memory, executive functioning, short-term and long-term memory, and visuospatial perception before surgery, prior to discharge, at 3-month follow-up and 6 years after surgery. We compared the performance of these patients to normative datasets. Results: Despite equivalent levels of pre-surgery performance between patients, oncology patients exceeded their preoperative neurocognitive levels, suggesting less postoperative cognitive dysfunction in orthopedic patients overall, in all neuropsychological domains at a 6-year follow-up, except short-term retention. In contrast, orthopedic patients showed no improvement, and, instead, showed some cognitive decline, which remained consistent over time. Conclusions: Our findings highlight the critical role of the type of surgery utilized in the development of POCD and have implications for clinical management and patients’ quality of life in the very long term. Health policy professionals should be aware that patients’ low POCD may persist in the long term, and this is useful from a clinician’s point of view.https://doi.org/10.1177/26331055231220906 |
| spellingShingle | Kalliopi Megari Evanthia Thomaidou Georgios A. Kougioumtzis Maria Theodoratou Dimitra Katsarou Eleni Karlafti Matthaios Didaggelos Daniel Paramythiotis Eleni Argyriadou What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original Research Neuroscience Insights |
| title | What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original Research |
| title_full | What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original Research |
| title_fullStr | What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original Research |
| title_full_unstemmed | What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original Research |
| title_short | What Do Cancer Surgery and orthopedic Surgery Elderly Patients Have in Common? A Long-term Postoperative Cognitive Dysfunction in Orthopedic and Cancer Patients Original Research |
| title_sort | what do cancer surgery and orthopedic surgery elderly patients have in common a long term postoperative cognitive dysfunction in orthopedic and cancer patients original research |
| url | https://doi.org/10.1177/26331055231220906 |
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