A Review of Electrochemical Electrodes and Readout Interface Designs for Biosensors

Electrochemical detection is widely used in biosensing fields, such as medical diagnosis and health monitoring due to its real-time response and high accuracy. Both passive and active electrodes and the corresponding readout circuits have been continuously improved over the past decades. This articl...

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Main Authors: Yuan Ma, Yuping Deng, Chao Xie, Bingjing Zhang, Boyu Shen, Milin Zhang, Lan Yin, Xilin Liu, Jan van der Spiegel
Format: Article
Language:English
Published: IEEE 2023-01-01
Series:IEEE Open Journal of the Solid-State Circuits Society
Subjects:
Online Access:https://ieeexplore.ieee.org/document/9950234/
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author Yuan Ma
Yuping Deng
Chao Xie
Bingjing Zhang
Boyu Shen
Milin Zhang
Lan Yin
Xilin Liu
Jan van der Spiegel
author_facet Yuan Ma
Yuping Deng
Chao Xie
Bingjing Zhang
Boyu Shen
Milin Zhang
Lan Yin
Xilin Liu
Jan van der Spiegel
author_sort Yuan Ma
collection DOAJ
description Electrochemical detection is widely used in biosensing fields, such as medical diagnosis and health monitoring due to its real-time response and high accuracy. Both passive and active electrodes and the corresponding readout circuits have been continuously improved over the past decades. This article summarizes the redox reaction method, state-of-the-art electrode materials, and readout circuits based on the passive three-electrode. The redox-current-based readout circuits are widely used and developed toward multichannel high precision and low power consumption. In terms of active electrodes, this article reviews the development of field-effect transistors (FETs)-based electrochemical detection and readout circuits. In the past decade, the development of organic electrochemical transistors (OECTs) has also enabled more precise electrochemical detection.
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spelling doaj.art-08463d0596d54d3db927b043cdd28a922024-04-22T20:40:24ZengIEEEIEEE Open Journal of the Solid-State Circuits Society2644-13492023-01-013768810.1109/OJSSCS.2022.32219249950234A Review of Electrochemical Electrodes and Readout Interface Designs for BiosensorsYuan Ma0https://orcid.org/0000-0002-6445-3741Yuping Deng1Chao Xie2Bingjing Zhang3Boyu Shen4https://orcid.org/0000-0001-8696-916XMilin Zhang5https://orcid.org/0000-0001-6915-0734Lan Yin6Xilin Liu7https://orcid.org/0000-0002-9547-3905Jan van der Spiegel8https://orcid.org/0000-0002-6070-0717Department of Electronic Engineering, Tsinghua University, Beijing, ChinaSchool of Materials Science and Engineering, Tsinghua University, Beijing, ChinaDepartment of Electronic Engineering, Tsinghua University, Beijing, ChinaDepartment of Electronic Engineering, Tsinghua University, Beijing, ChinaSchool of Materials Science and Engineering, Tsinghua University, Beijing, ChinaDepartment of Electronic Engineering, Tsinghua University, Beijing, ChinaSchool of Materials Science and Engineering, Tsinghua University, Beijing, ChinaDepartment of Electrical and Computer Engineering, University of Toronto, Toronto, CanadaDepartment of Electrical and Systems Engineering, University of Pennsylvania, Philadelphia, PA, USAElectrochemical detection is widely used in biosensing fields, such as medical diagnosis and health monitoring due to its real-time response and high accuracy. Both passive and active electrodes and the corresponding readout circuits have been continuously improved over the past decades. This article summarizes the redox reaction method, state-of-the-art electrode materials, and readout circuits based on the passive three-electrode. The redox-current-based readout circuits are widely used and developed toward multichannel high precision and low power consumption. In terms of active electrodes, this article reviews the development of field-effect transistors (FETs)-based electrochemical detection and readout circuits. In the past decade, the development of organic electrochemical transistors (OECTs) has also enabled more precise electrochemical detection.https://ieeexplore.ieee.org/document/9950234/Ion-selective field-effect transistor (ISFET)organic electrochemical transistor (OECT)potentiostatthree-electrode systemtransimpedance amplifier (TIA)
spellingShingle Yuan Ma
Yuping Deng
Chao Xie
Bingjing Zhang
Boyu Shen
Milin Zhang
Lan Yin
Xilin Liu
Jan van der Spiegel
A Review of Electrochemical Electrodes and Readout Interface Designs for Biosensors
IEEE Open Journal of the Solid-State Circuits Society
Ion-selective field-effect transistor (ISFET)
organic electrochemical transistor (OECT)
potentiostat
three-electrode system
transimpedance amplifier (TIA)
title A Review of Electrochemical Electrodes and Readout Interface Designs for Biosensors
title_full A Review of Electrochemical Electrodes and Readout Interface Designs for Biosensors
title_fullStr A Review of Electrochemical Electrodes and Readout Interface Designs for Biosensors
title_full_unstemmed A Review of Electrochemical Electrodes and Readout Interface Designs for Biosensors
title_short A Review of Electrochemical Electrodes and Readout Interface Designs for Biosensors
title_sort review of electrochemical electrodes and readout interface designs for biosensors
topic Ion-selective field-effect transistor (ISFET)
organic electrochemical transistor (OECT)
potentiostat
three-electrode system
transimpedance amplifier (TIA)
url https://ieeexplore.ieee.org/document/9950234/
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