Precise Diabetic Wound Therapy: PLS Nanospheres Eliminate Senescent Cells via DPP4 Targeting and PARP1 Activation
Abstract Diabetic ulcers, a difficult problem faced by clinicians, are strongly associated with an increase in cellular senescence. Few empirical studies have focused on exploring a targeted strategy to cure diabetic wounds by eliminating senescent fibroblasts (SFs) and reducing side effects. In thi...
Main Authors: | Renliang Zhao, Xiangyun Jin, Ang Li, Bitong Xu, Yifan Shen, Wei Wang, Jinghuan Huang, Yadong Zhang, Xiaolin Li |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-01-01
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Series: | Advanced Science |
Subjects: | |
Online Access: | https://doi.org/10.1002/advs.202104128 |
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