Target blood pressure levels in patients with arterial hypertension and frailty
Arterial hypertension (AH) is an important public health problem worldwide. The high prevalence of hypertension can partially be explained by an increase in blood pressure (BP) with age and a rapid increase in the elderly population (over 65 years old). Despite the effect of age on BP, evidence of t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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IP Morozov P.V.
2019-12-01
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| Series: | Системные гипертензии |
| Subjects: | |
| Online Access: | https://syst-hypertension.ru/2075-082X/article/viewFile/33555/pdf |
| _version_ | 1818944644735565824 |
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| author | Olga D Ostroumova Marina S Cherniaeva Alexandr P Morozov |
| author_facet | Olga D Ostroumova Marina S Cherniaeva Alexandr P Morozov |
| author_sort | Olga D Ostroumova |
| collection | DOAJ |
| description | Arterial hypertension (AH) is an important public health problem worldwide. The high prevalence of hypertension can partially be explained by an increase in blood pressure (BP) with age and a rapid increase in the elderly population (over 65 years old). Despite the effect of age on BP, evidence of target blood pressure values for its control in patients of older age groups with AH is limited, especially if they have frailty. There are data from a number of studies that reveal a relationship between lower BP levels and all-cause mortality in patients with AH in older age groups. In clinical practice, decisions regarding BP targets are especially difficult in elderly people with frailty who often do not meet the criteria for inclusion in randomized controlled trials and for this group of elderly people the clinical recommendations of leading communities do not give a specific answer about the target BP level. The evidence base regarding the target BP values in the treatment of AH in patients of older age groups with frailty presented in this review is not numerous, but its analysis suggests the advantages of higher BP numbers, with maximum systolic BP values of 165 mm Hg and diastolic BP of 90 mm Hg, while lower BP levels may be unsafe in terms of increasing the risk of adverse cardiovascular events and mortality from both cardiovascular causes and all causes. Polymorbidity in combination with polypharmacy and an increased risk of adverse events require a patient-oriented individual approach to the appointment of antihypertensive therapy. For a final decision on the management tactics of patients with AH and frailty, large, specially designed randomized clinical trials are needed. |
| first_indexed | 2024-12-20T07:46:30Z |
| format | Article |
| id | doaj.art-0849d019d0514f6688d654211c2a4985 |
| institution | Directory Open Access Journal |
| issn | 2075-082X 2542-2189 |
| language | Russian |
| last_indexed | 2024-12-20T07:46:30Z |
| publishDate | 2019-12-01 |
| publisher | IP Morozov P.V. |
| record_format | Article |
| series | Системные гипертензии |
| spelling | doaj.art-0849d019d0514f6688d654211c2a49852022-12-21T19:47:57ZrusIP Morozov P.V.Системные гипертензии2075-082X2542-21892019-12-01164526010.26442/2075082X.2019.4.19057730285Target blood pressure levels in patients with arterial hypertension and frailtyOlga D Ostroumova0Marina S Cherniaeva1Alexandr P Morozov2Pirogov Russian National Research Medical UniversityCentral State Medical Academy of the President of the Russian Federation; Hospital for War Veterans №2Hospital for War Veterans №2Arterial hypertension (AH) is an important public health problem worldwide. The high prevalence of hypertension can partially be explained by an increase in blood pressure (BP) with age and a rapid increase in the elderly population (over 65 years old). Despite the effect of age on BP, evidence of target blood pressure values for its control in patients of older age groups with AH is limited, especially if they have frailty. There are data from a number of studies that reveal a relationship between lower BP levels and all-cause mortality in patients with AH in older age groups. In clinical practice, decisions regarding BP targets are especially difficult in elderly people with frailty who often do not meet the criteria for inclusion in randomized controlled trials and for this group of elderly people the clinical recommendations of leading communities do not give a specific answer about the target BP level. The evidence base regarding the target BP values in the treatment of AH in patients of older age groups with frailty presented in this review is not numerous, but its analysis suggests the advantages of higher BP numbers, with maximum systolic BP values of 165 mm Hg and diastolic BP of 90 mm Hg, while lower BP levels may be unsafe in terms of increasing the risk of adverse cardiovascular events and mortality from both cardiovascular causes and all causes. Polymorbidity in combination with polypharmacy and an increased risk of adverse events require a patient-oriented individual approach to the appointment of antihypertensive therapy. For a final decision on the management tactics of patients with AH and frailty, large, specially designed randomized clinical trials are needed.https://syst-hypertension.ru/2075-082X/article/viewFile/33555/pdfarterial hypertensiontarget blood pressureolder agefrailty |
| spellingShingle | Olga D Ostroumova Marina S Cherniaeva Alexandr P Morozov Target blood pressure levels in patients with arterial hypertension and frailty Системные гипертензии arterial hypertension target blood pressure older age frailty |
| title | Target blood pressure levels in patients with arterial hypertension and frailty |
| title_full | Target blood pressure levels in patients with arterial hypertension and frailty |
| title_fullStr | Target blood pressure levels in patients with arterial hypertension and frailty |
| title_full_unstemmed | Target blood pressure levels in patients with arterial hypertension and frailty |
| title_short | Target blood pressure levels in patients with arterial hypertension and frailty |
| title_sort | target blood pressure levels in patients with arterial hypertension and frailty |
| topic | arterial hypertension target blood pressure older age frailty |
| url | https://syst-hypertension.ru/2075-082X/article/viewFile/33555/pdf |
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