Integrated single-cell and bulk RNA sequencing reveals CREM is involved in the pathogenesis of ulcerative colitis

Integrated single-cell and bulk RNA sequencing reveals CREM is involved in the pathogenesis of ulcerative colitis

Background: Ulcerative colitis (UC) is an inflammatory bowel disease characterized by persistent colonic inflammation. Here, we performed a systematic analysis to gain better insights into UC pathogenesis. Methods: We analyzed two UC-related datasets extracted from the gene expression omnibus databa...

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Bibliographic Details
Main Authors: Zongqi He, Qing Zhou, Jun Du, Yuyu Huang, Bensheng Wu, Zhizhong Xu, Chao Wang, Xudong Cheng
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Heliyon
Subjects:
Ulcerative colitis
Single-cell
RNA sequencing
Immune
Transcription factors
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024038362

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