The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health
Spirulina is a popular herbal food that has a preventive effect on health. In the study, it aimed to evaluate the effects of different doses of Spirulina platensis (Arthrospira platensis) on the morphological properties of the duodenum of rats, and to assign the effect of Spirulina on the expression...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2022-09-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453022000659 |
| _version_ | 1797726058022174720 |
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| author | Ender Deniz Asmaz Nilay Seyidoglu |
| author_facet | Ender Deniz Asmaz Nilay Seyidoglu |
| author_sort | Ender Deniz Asmaz |
| collection | DOAJ |
| description | Spirulina is a popular herbal food that has a preventive effect on health. In the study, it aimed to evaluate the effects of different doses of Spirulina platensis (Arthrospira platensis) on the morphological properties of the duodenum of rats, and to assign the effect of Spirulina on the expression of proliferating cell nuclear antigen (PCNA) in the rat duodenum, and thereby to observe the effects on intestinal health. 30 male Wistar albino rats were divided into 3 groups for 45 days. The first group was received the basal diet; the second group was given 500 mg/kg Spirulina daily by oral gavage; the third group was given 1000 mg/kg Spirulina daily. The duodenum segments were taken at the end of the trial and processed for histological assay. Although the total mucosa, villus height and villus/cript ratio were found higher in high dose Spirulina, the lower cript depth was detected in same group compared to control and low dose group. A significant increase was observed at high dose compared to the control and low dose group in terms of PCNA expression intensity and proliferation index. Findings suggest that high dose of Spirulina may support the duodenal growth, and thereby intestinal health. |
| first_indexed | 2024-03-12T10:40:20Z |
| format | Article |
| id | doaj.art-084f2866fbf74cc58c03834c0736c1e5 |
| institution | Directory Open Access Journal |
| issn | 2213-4530 |
| language | English |
| last_indexed | 2024-03-12T10:40:20Z |
| publishDate | 2022-09-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj.art-084f2866fbf74cc58c03834c0736c1e52023-09-02T08:09:08ZengTsinghua University PressFood Science and Human Wellness2213-45302022-09-0111513421346The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal healthEnder Deniz Asmaz0Nilay Seyidoglu1Department of Histology and Embryology, Veterinary Faculty, Bursa Uludag University, Nilufer 16059, TurkeyDepartment of Physiology, Veterinary Faculty, Tekirdag Namik Kemal University, Suleymanpasa 59030, Turkey; Corresponding author at: Department of Physiology, Veterinary Faculty, Tekirdag Namik Kemal University, Suleymanpasa 59030, Turkey.Spirulina is a popular herbal food that has a preventive effect on health. In the study, it aimed to evaluate the effects of different doses of Spirulina platensis (Arthrospira platensis) on the morphological properties of the duodenum of rats, and to assign the effect of Spirulina on the expression of proliferating cell nuclear antigen (PCNA) in the rat duodenum, and thereby to observe the effects on intestinal health. 30 male Wistar albino rats were divided into 3 groups for 45 days. The first group was received the basal diet; the second group was given 500 mg/kg Spirulina daily by oral gavage; the third group was given 1000 mg/kg Spirulina daily. The duodenum segments were taken at the end of the trial and processed for histological assay. Although the total mucosa, villus height and villus/cript ratio were found higher in high dose Spirulina, the lower cript depth was detected in same group compared to control and low dose group. A significant increase was observed at high dose compared to the control and low dose group in terms of PCNA expression intensity and proliferation index. Findings suggest that high dose of Spirulina may support the duodenal growth, and thereby intestinal health.http://www.sciencedirect.com/science/article/pii/S2213453022000659HistochemistryDuodenumSpirulina platensisIntestinal health |
| spellingShingle | Ender Deniz Asmaz Nilay Seyidoglu The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health Food Science and Human Wellness Histochemistry Duodenum Spirulina platensis Intestinal health |
| title | The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health |
| title_full | The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health |
| title_fullStr | The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health |
| title_full_unstemmed | The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health |
| title_short | The prevention role of Spirulina platensis (Arthrospira platensis) on intestinal health |
| title_sort | prevention role of spirulina platensis arthrospira platensis on intestinal health |
| topic | Histochemistry Duodenum Spirulina platensis Intestinal health |
| url | http://www.sciencedirect.com/science/article/pii/S2213453022000659 |
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