Impact of baseline culture conditions of cancer organoids when determining therapeutic response and tumor heterogeneity

Impact of baseline culture conditions of cancer organoids when determining therapeutic response and tumor heterogeneity

Abstract Representative models are needed to screen new therapies for patients with cancer. Cancer organoids are a leap forward as a culture model that faithfully represents the disease. Mouse-derived cancer organoids (MDCOs) are becoming increasingly popular, however there has yet to be a standardi...

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Bibliographic Details
Main Authors: Rebecca A. DeStefanis, Jeremy D. Kratz, Autumn M. Olson, Aishwarya Sunil, Alyssa K. DeZeeuw, Amani A. Gillette, Gioia C. Sha, Katherine A. Johnson, Cheri A. Pasch, Linda Clipson, Melissa C. Skala, Dustin A. Deming
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08937-z

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