miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner
Apoptotic cell death of cardiomyocytes is a characteristic hallmark of ischemia–reperfusion (I/R) injury. The master <i>hypoxamiR</i>, microRNA-210 (miR-210), is considered the primary driver of the cellular response to hypoxic stress. However, to date, no consensus has emerged with rega...
Main Authors: | Gurdeep Marwarha, Øystein Røsand, Nathan Scrimgeour, Katrine Hordnes Slagsvold, Morten Andre Høydal |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/10/1/42 |
Similar Items
-
NF-κB Transcriptional Activity Indispensably Mediates Hypoxia–Reoxygenation Stress-Induced microRNA-210 Expression
by: Gurdeep Marwarha, et al.
Published: (2023-04-01) -
GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia
by: Gurdeep Marwarha, et al.
Published: (2022-08-01) -
Hypoxia/reoxygenation-induced myocardial lesions in newborn piglets are related to interindividual variability and not to oxygen concentration
by: Armando Faa, et al.
Published: (2012-01-01) -
PDRPS7 protects cardiac cells from hypoxia/reoxygenation injury through inactivation of JNKs
by: Yulian Duan, et al.
Published: (2020-04-01) -
Hydrogen Sulfide Attenuates Myocardial Hypoxia-Reoxygenation Injury by Inhibiting Autophagy via mTOR Activation
by: Jian Xiao, et al.
Published: (2015-12-01)